Evidence map›Paper›PMID 42252698›Full record

ArticleJournal of sleep research2026

Obstructive Sleep Apnea and Cognitive Impairment: Implications for Surgical Outcomes.

Yasmin Alhamdah, Ellene Yan, Paras Kapoor, Aparna Saripella, Nina Butris, David He, Leif Erik Lovblom, Sazzadul Islam, Jean Wong, Frances Chung

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of sleep research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yasmin AlhamdahDepartment of Anesthesia and Pain Management, Toronto Western Hospital, University Health Network, University of Toronto, Toronto, Ontario, Canada.
Ellene YanDepartment of Anesthesia and Pain Management, Toronto Western Hospital, University Health Network, University of Toronto, Toronto, Ontario, Canada.
Paras KapoorDepartment of Anesthesia and Pain Management, Toronto Western Hospital, University Health Network, University of Toronto, Toronto, Ontario, Canada.
Aparna SaripellaDepartment of Anesthesia and Pain Management, Toronto Western Hospital, University Health Network, University of Toronto, Toronto, Ontario, Canada.
Nina ButrisDepartment of Anesthesia and Pain Management, Toronto Western Hospital, University Health Network, University of Toronto, Toronto, Ontario, Canada.
David HeInstitute of Medical Science, Temerty Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.
Leif Erik LovblomBiostatistics Department, University Health Network, Toronto, Ontario, Canada.ORCID https://orcid.org/0000-0002-6774-8924
Sazzadul IslamDepartment of Anesthesia and Pain Management, Toronto Western Hospital, University Health Network, University of Toronto, Toronto, Ontario, Canada.
Jean WongDepartment of Anesthesia and Pain Management, Toronto Western Hospital, University Health Network, University of Toronto, Toronto, Ontario, Canada.
Frances ChungDepartment of Anesthesia and Pain Management, Toronto Western Hospital, University Health Network, University of Toronto, Toronto, Ontario, Canada.

Funding

CIHR FBD-195197Margaret & Howard Gamble Research GrantOntario Graduate ScholarshipOntario Ministry of Health and Long-Term Care Innovation FundResMed Foundation G-575225462760University Health Network Foundation G-585005300860
6 · The paper itself

Abstract

The influence of coexisting obstructive sleep apnea (OSA) and cognitive impairment (CI) on perioperative outcomes is unclear, despite its potential clinical significance. We aimed to compare clinical outcomes between surgical patients with OSA or high risk OSA (OSA/HR-OSA) who have CI and those without CI. We assessed 655 surgical patients aged ≥ 65 years. All participants completed the STOP or STOP-Bang questionnaires to assess for risk of OSA and were classified as OSA/HR-OSA or No-OSA/LR-OSA. To assess for probable CI, participants completed the in-person or telephone Montreal Cognitive Assessment (MoCA) and were classified as CI or No-CI. Among 655 participants, 377 (57.6%) had OSA/HR-OSA and 216 (33.0%) had CI. Twenty-one percent (137/655) presented with coexisting OSA/HR-OSA and CI. More participants in the OSA/HR-OSA group had CI compared to the No-OSA/LR-OSA group (36.3% vs. 28.4%, p = 0.041). After adjustment, each additional year of education was associated with a 12% decrease in the odds of CI among participants with OSA/HR-OSA (p < 0.001). Participants with coexisting OSA/HR-OSA and CI had about 2-fold higher odds for all-cause complications (OR: 2.01, 95% CI: 1.29, 3.13, p = 0.002) and 80% higher adverse composite outcomes (OR: 1.79, 95% CI: 1.16, 2.79, p = 0.009) at 30 days postoperatively than those with OSA/HR-OSA and No-CI, after adjustment for covariates. In conclusion, coexisting OSA/HR-OSA and CI was common at 21% and associated with increased 30-day all-cause complications and composite outcomes. These findings emphasise the need for enhanced preoperative screening and multidisciplinary strategies to identify and manage such vulnerable patients.

Indexed as

Cognitive DysfunctionPostoperative ComplicationsSleep Apnea, ObstructiveAgedFemaleHumansMaleSurveys and QuestionnairesTreatment Outcomeadverse outcomescognitionolder patientssleep disordersSTOP‐bang questionnairesurgery

Identifiers

PMID42252698
PMCPMC13619048

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.