Evidence map›Paper›PMID 42252638›Full record

ReviewMolecular reproduction and development2026

Sex Determination in Sponges.

Jose M Lorente-Sorolla, Ana Riesgo

Abstract readReview
In one paragraph

Review in Molecular reproduction and development, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Jose M Lorente-SorollaDepartment of Biodiversity and Evolutionary Biology, Museo Nacional de Ciencias Naturales (CSIC), Madrid, Spain.ORCID 0000-0002-4942-0255
Ana RiesgoDepartment of Biodiversity and Evolutionary Biology, Museo Nacional de Ciencias Naturales (CSIC), Madrid, Spain.

Funding

Biodiversa+ SponBIODIVBiodiversity Genomics Europe 101059492Fundación BiodiversidadFundaciÓn BiodiversidadMinisterio de Universidades PID2019-105769GB-I00Ministerio de Universidades RYC2018-024247-I
6 · The paper itself

Abstract

Sex determination in Porifera remains one of the least understood aspects of early metazoan biology despite the group's key phylogenetic position. Sponges display exceptional diversity in sexual systems-ranging from stable gonochorism to sequential hermaphroditism and sex reversal-yet lack morphological dimorphism and any discrete gonadal structures, blurring the boundary between sex determination and gametogenesis. Here we synthesize current knowledge on sexual systems, environmental and genetic influences on sexual fate, and the evolutionary origins of sexual systems in sponges. Evidence for environmental modulation is substantial, particularly temperature-driven shifts in sex ratios and reproductive timing, but environmental sex determination remains unsupported by causal evidence yet. Conversely, conserved molecular components of metazoan sex-determining pathways, such as fem-1 and Dmrt genes, are present in several sponge lineages, though their functional roles remain unresolved. We also evaluate the hypothesis that microbial symbionts contribute to sexual allocation by buffering the energetic costs of gametogenesis. Overall, sponges exhibit an evolutionarily labile system in which sexual fate may emerge from the interaction of conserved genetic modules, environmental cues, and physiological constraints. Clarifying these mechanisms will be essential for understanding the origins of sex determination in Metazoa and for predicting reproductive resilience under environmental change.

Indexed as

GametogenesisPoriferaSex Determination ProcessesAnimalsBiological EvolutionFemaleenvironmental sex determinationgametogenesisgenotypic sex determinationgonochorismsex determinationsponges

Identifiers

PMID42252638
PMCPMC13243818

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.