Evidence map›Paper›PMID 42252607›Full record

ArticleAnnals of clinical and translational neurology2026

T

Sarah J Wright, Scotty G McKay, Jean Ramos Bou, Fen Bao, Vivian B Truong, Chenyang Li, Li Jiang, Anza B Memon, E Mark Haacke, Yulin Ge and 1 more

Abstract read
In one paragraph

Article in Annals of clinical and translational neurology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Sarah J WrightDepartment of Neurology, Wayne State University School of Medicine, Detroit, Michigan, USA.
Scotty G McKayDepartment of Radiology, Wayne State University School of Medicine, Detroit, Michigan, USA.
Jean Ramos BouDepartment of Radiology, Wayne State University School of Medicine, Detroit, Michigan, USA.
Fen BaoDepartment of Neurology, Wayne State University School of Medicine, Detroit, Michigan, USA.
Vivian B TruongDepartment of Neurology, Wayne State University School of Medicine, Detroit, Michigan, USA.
Chenyang LiDepartment of Radiology, NYU Grossman School of Medicine, New York, New York, USA.
Li JiangDepartment of Radiology, NYU Grossman School of Medicine, New York, New York, USA.
Anza B MemonDepartment of Neurology, Wayne State University School of Medicine, Detroit, Michigan, USA.
E Mark HaackeDepartment of Radiology, Wayne State University School of Medicine, Detroit, Michigan, USA.
Yulin GeDepartment of Radiology, NYU Grossman School of Medicine, New York, New York, USA.
Yongsheng ChenDepartment of Neurology, Wayne State University School of Medicine, Detroit, Michigan, USA.ORCID https://orcid.org/0000-0001-7114-5731

Funding

ACQUIRING A 3T PRISMA FOR NEUROSCIENCE RESEARCH AT WSUS10OD028724 · OD · WAYNE STATE UNIVERSITY · PI HAACKE, EWART MARK · 2022 to 2022
$2.0M
Biomarker development in patients with HNPPR61NS119434 · NINDS · WAYNE STATE UNIVERSITY · PI CHEN, YONGSHENG, LI, JUN · 2022 to 2024
$1.4M
National Institutes of Health (NIH) R61NS119434NIH HHS S10 OD028724NINDS NIH HHS R61 NS119434
6 · The paper itself

Abstract

objectiveDifferentiating remyelinated from demyelinated lesions in MS remains challenging without histological confirmation. This study introduces the T

methodsThirty individuals with MS (mean age: 47.5 ± 11.5 years) underwent 3 T MRI using 3D gradient-echo qMRI sequences to generate quantitative maps of T

resultsWe found that hyperintense lesions on TPR exhibited significantly higher T

interpretationIn summary, TPR imaging visually differentiates MS lesions into hyper-, hypo-, and iso-intense categories, whereas all lesions appear hyperintense on FLAIR. Hyperintense TPR lesions correspond to increased water and reduced myelin content, as confirmed by quantitative T

Indexed as

demyelinationmultiple sclerosisquantitative MRIremyelinationT1 mapping

Identifiers

PMID42252607
PMCPMC13394161

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.