SynthesisBJOG : an international journal of obstetrics and gynaecology2026
Association Between Lateral Placenta and Adverse Maternal and Perinatal Outcomes: A Systematic Review and Meta-Analysis.
Synthesis in BJOG : an international journal of obstetrics and gynaecology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
backgroundAdverse maternal and perinatal outcomes such as preeclampsia, small-for-gestational age (SGA) and preterm birth remain major global health concerns. Beyond known high-risk placental features, emerging evidence suggests lateral placenta to be associated with impaired uteroplacental blood flow resulting in placenta dysfunction and adverse outcomes. A better understanding of these associations requires synthesizing both crude and adjusted effect estimates from available evidence.
objectivesTo comprehensively review and synthesize available evidence on the association between lateral placenta and adverse maternal and perinatal outcomes. SEARCH STRATEGY: MEDLINE (PubMed), EMBASE, Scopus and Cochrane CENTRAL were searched on 25th August, 2025. SELECTION CRITERIA: Studies that assessed the association between lateral placentation and adverse maternal and perinatal outcomes in singleton pregnancies. DATA COLLECTION AND ANALYSIS: Data were independently extracted by two reviewers. The random-effects model was used to pool estimates of both crude and adjusted odds ratios (ORs) with corresponding 95% confidence interval (CI). Statistical heterogeneity was assessed by the I MAIN
resultsTwenty one eligible studies with a total of 162 727 singleton pregnancies were included in the meta-analyses. Lateral placenta was associated with preeclampsia (OR = 1.65, 95% CI: 1.25, 2.19, I
conclusionsLateral placenta is associated with increased odds of preeclampsia, SGA, preterm birth, non-vertex foetal presentation, and retained placenta. After controlling for confounders, lateral placenta remained independently associated with increased odds of SGA, preterm birth, and retained placenta. More studies that adjust for confounders are, however, needed to further clarify and strengthen the evidence base of this independent association.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.