ArticleAlzheimer's & dementia : the journal of the Alzheimer's Association2026
Differential associations of plasma biomarkers with Alzheimer's disease and small vessel disease: A multimodal imaging study.
Article in Alzheimer's & dementia : the journal of the Alzheimer's Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Differential associations of plasma biomarkers with Alzheimer's disease and small vessel disease: A multimodal imaging study.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Clinical variables provide the main predictive signal for early in-hospital rehabilitation triage after small-artery occlusion stroke: development and internal validation of an interpretable model.Frontiers in neurology · 2026Article
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Authors and funding
21 authors.
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Abstract
introductionWe investigated how plasma biomarkers (phosphorylated tau 217 [ptau
methods76 memory clinic patients underwent plasma biomarker assessment, neuropsychological testing, and 3T MRI. SVD burden was assessed using white matter hyperintensity (WMH) volume, mean skeletonized mean diffusivity (MSMD), and fiber density. AD-related neurodegeneration was captured by AD-signature cortical thickness and fiber-bundle cross-section. Findings were validated in 41 Alzheimer's Disease Neuroimaging Initiative (ADNI) participants with amyloid-/tau-positron emission tomography (PET).
resultsAssociations varied between biomarkers. NfL showed strongest associations with SVD burden, ptau DISCUSSION: NfL relates to SVD burden, while ptau
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