Evidence map›Paper›PMID 42252457›Full record

ArticleHarm reduction journal2026

Participant perspectives on a safe supply program in Vancouver, Canada: impacts, satisfaction and improvement priorities.

Zia Mawani, Mary Clare Kennedy, Elizabeth Holliday, Christy Sutherland, Thomas Kerr

Abstract read
In one paragraph

Article in Harm reduction journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Zia MawaniBritish Columbia Centre on Substance Use, St. Paul's Hospital, 2. 400-1045 Howe Street, Vancouver, BC, V6Z 2A9, Canada.
Mary Clare KennedyBritish Columbia Centre on Substance Use, St. Paul's Hospital, 2. 400-1045 Howe Street, Vancouver, BC, V6Z 2A9, Canada.
Elizabeth HollidayVancouver Coastal Health, Vancouver, BC, Canada.
Christy SutherlandPHS Community Services Society, Vancouver, BC, Canada.
Thomas KerrBritish Columbia Centre on Substance Use, St. Paul's Hospital, 2. 400-1045 Howe Street, Vancouver, BC, V6Z 2A9, Canada. bccsu-tk@bccsu.ubc.ca.

Funding

Canada Research Chairs RC-2021-00272
6 · The paper itself

Abstract

objectivesThe ongoing toxic drug crisis in Canada, driven largely by fentanyl proliferation, has led to ever-escalating overdose rates. The Safer Alternatives for Emergency Response (SAFER) program was launched in Vancouver, British Columbia (BC) in 2021 to reduce overdose risk by offering prescribed pharmaceutical alternatives, including fentanyl medications. This study aimed to evaluate satisfaction and the program's perceived impact on health and social outcomes among SAFER participants.

methodsData were collected from 78 SAFER participants through baseline interviewer-administered questionnaires. The primary outcome was self-reported changes in drug use, health status and social outcomes. Descriptive statistics summarized participant characteristics and outcomes.

resultsAmong 78 participants, with 22 (28%) identifying as women or gender diverse, 76% reported reduced drug use, while 71% experienced reductions in drug cravings/withdrawal and overdose risk, respectively. Safer drug-use behaviours were also reported: 56% reported that they were more likely to use sterile equipment, 37% said they were more likely to check their drugs, and 35% said they were more likely to carry naloxone. Improvements in overall physical health (58%), mental health (63%), financial stability (55%), and social connections (49%) were also noted. High satisfaction with services was reported (78%), although 71% suggested improvements, including extended hours, easier access to carry doses, and expanded medication options. DISCUSSION: These findings indicate that the SAFER program is perceived as effective in reducing overdose risk and improving health and social outcomes. However, barriers such as service accessibility and limited medication options remain. Addressing these concerns could enhance program outcomes. Further large-scale research is recommended to confirm these results and explore long-term impacts.

Indexed as

Drug OverdoseFentanylHarm ReductionOpioid-Related DisordersPatient SatisfactionAdultAnalgesics, OpioidBritish ColumbiaFemaleHumansMaleMiddle AgedNaloxoneNarcotic AntagonistsSurveys and QuestionnairesYoung AdultAnalgesics, OpioidFentanylNaloxoneNarcotic AntagonistsHarm reductionOpioid epidemicOverdose preventionPublic healthSafer supplySubstance use disorder

Identifiers

PMID42252457
PMCPMC13465644

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.