Evidence map›Paper›PMID 42252137›Full record

ArticleBMJ open2026

Feasibility of NIV-NAVA as a primary respiratory support and its clinical impacts in a targeted group of preterm infants: protocol for a prospective observational study.

Hannah Cho, Young Hwa Jung, Jiseon Park, Hyo Ju Yang, Mi Jin Kim, Juyoung Lee

Registry-linked trialAbstract read
In one paragraph

Article in BMJ open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06786039 (Clinical Impact of Non-invasive Neurally Adjusted Ventilatory Assist in Very Preterm Infants), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06786039 recruitingnot on this map

Clinical Impact of Non-invasive Neurally Adjusted Ventilatory Assist in Very Preterm Infants

Typeobservational_patient_registrySponsorKorea University Anam HospitalRan2025 to 2030Enrolled80ConditionsPreterm InfantArmsNon-invasive NAVA
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hannah ChoDepartment of Pediatrics, Korea University College of Medicine, Seoul, Korea (the Republic of).
Young Hwa JungDepartment of Pediatrics, Seoul National University College of Medicine, Seoul, Korea (the Republic of).
Jiseon ParkDepartment of Pediatrics, Korea University College of Medicine, Seoul, Korea (the Republic of).
Hyo Ju YangDepartment of Pediatrics, Seoul National University Bundang Hospital, Seongnam-si, Gyeonggi-do, Korea (the Republic of).
Mi Jin KimDepartment of Pediatrics, Seoul National University Bundang Hospital, Seongnam-si, Gyeonggi-do, Korea (the Republic of).
Juyoung LeeDepartment of Pediatrics, Korea University College of Medicine, Seoul, Korea (the Republic of) juyounglee@korea.ac.kr.ORCID http://orcid.org/0000-0001-7548-2284

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionNon-invasive neurally adjusted ventilatory assist (NIV-NAVA) is a promising respiratory support method for avoiding invasive mechanical ventilation in neonatal intensive care units (NICUs). However, its effectiveness and safety have not been widely established through clinical evidence. In this study, we aim to evaluate the feasibility of NIV-NAVA as a primary respiratory support method after birth and its effects on short-term clinical outcomes and long-term neurodevelopment in preterm infants. METHODS AND ANALYSIS: In this prospective multicentre observational study, 230 preterm infants will be recruited after birth. This study will include preterm infants born between 27 ETHICS AND DISSEMINATION: The Institutional Review Board (IRB) of Korea University Anam Hospital (2024AN0554) and Seoul National University Bundang Hospital (IRB No. B-2507-984-304) approved this study. The results will be disseminated through scientific conferences and publications. TRIAL REGISTRATION NUMBER: NCT06786039 registered on 14 January 2025.

Indexed as

Infant, PrematureInteractive Ventilatory SupportNoninvasive VentilationRespiratory Distress Syndrome, NewbornContinuous Positive Airway PressureFeasibility StudiesFemaleGestational AgeHumansInfant, NewbornIntensive Care Units, NeonatalMaleMulticenter Studies as TopicNeurodevelopmentObservational Studies as TopicProspective StudiesChild DevelopmentInteractive Ventilatory AssistNoninvasive VentilationPreterm Infants

Identifiers

PMID42252137
PMCPMC13250218

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.