Evidence map›Paper›PMID 42251492›Full record

ArticleAlzheimer's & dementia : the journal of the Alzheimer's Association2026

Implementing multidomain non-pharmaceutical interventions for preventing cognitive decline in community-dwelling older adults in China: An embedded mixed-methods implementation study of determinants and strategies.

Zishuo Huang, Gonghang Qiu, Changmiao Shi, Rong Chen, Erxu Xue, Ziyi Wang, Dong Roman Xu, Xinhua Ao, Ying Wang

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In one paragraph

Article in Alzheimer's & dementia : the journal of the Alzheimer's Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

9 authors.

Zishuo HuangSchool of Public Health, Fudan University, Shanghai, China.
Gonghang QiuSchool of Public Health, Fudan University, Shanghai, China.
Changmiao ShiChangxing Center for Disease Control and Prevention (Changxing Health Inspection Office), Changxing County, Huzhou City, Zhejiang, China.
Rong ChenChangxing Center for Disease Control and Prevention (Changxing Health Inspection Office), Changxing County, Huzhou City, Zhejiang, China.
Erxu XueThe D. H. Chen School of Universal Health, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Ziyi WangSchool of Public Health, Fudan University, Shanghai, China.
Dong Roman XuAcacia Lab for Implementation Science, SMU Institute for Global Health (SIGHT) and Center for World Health Organization Studies, School of Health Management and Dermatology Hospital of Southern Medical University (SMU), Guangzhou, China.
Xinhua AoChangxing County Health Bureau, Changxing County, Huzhou City, Zhejiang Province, China.
Ying WangSchool of Public Health, Fudan University, Shanghai, China.

Funding

Key Research and Development Program of Hunan Province of China 2017YFC1310504The Noncommunicable Chronic Diseases-National Science and Technology Major Project of the National Health Commission of China 2024ZD0524200The Noncommunicable Chronic Diseases-National Science and Technology Major Project of the National Health Commission of China 2024ZD0524203
6 · The paper itself

Abstract

introductionThe WW-FINGERS network has demonstrated the efficacy of multidomain non-pharmaceutical interventions (NPIs) but left their real-world implementation largely unexplored, prompting this study in Changxing County to identify key determinants and develop actionable strategies for community-based delivery.

methodsAn embedded mixed-methods retrospective evaluation using the Consolidated Framework for Implementation Research (CFIR) was conducted. Data from 42 stakeholders across six communities were analyzed via a hybrid deductive-inductive approach and coincidence analysis (CNA). Strategies were matched using the ERIC compendium and refined by a stakeholder panel.

resultsWe identified 202 determinants, revealing six core facilitator themes (e.g., policy-academia-community synergy) and six barrier themes(e.g., unsustainable funding). CNA delineated potential pathways. Three strategy bundles were finalized: Capacity Building, Collaborative Network Building, and an AI-enabled digital platform. DISCUSSION: This study provides a practical, theory-informed framework for implementing complex NPIs, bridging the science-to-practice gap in dementia prevention. The AI-enabled platform offers a forward-looking approach for sustained delivery.

Indexed as

Cognitive DysfunctionIndependent LivingAgedCapacity BuildingChinaFemaleHumansRetrospective Studiescognitive decline preventioncommunity‐dwelling older adultsConsolidated Framework for Implementation Research (CFIR)implementation sciencemultidomain non‐pharmaceutical interventions

Identifiers

PMID42251492
PMCPMC13242610

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.