Evidence map›Paper›PMID 42251417›Full record

ArticleChild and adolescent psychiatry and mental health2026

Social environmental risk factors for persistent self-harm in early-to-middle adolescence: data from the Tokyo Teen Cohort study.

Riki Tanaka, Atsushi Nishida, Daiki Nagaoka, Rin Minami, Akito Uno, Yutaka Sawai, Ayako Okuma, Satoshi Yamaguchi, Mitsuhiro Miyashita, Syudo Yamasaki and 2 more

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Article in Child and adolescent psychiatry and mental health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

12 authors.

Riki TanakaDepartment of Neuropsychiatry, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.
Atsushi NishidaResearch Center for Social Science and Medicine, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan.
Daiki NagaokaDepartment of Neuropsychiatry, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.
Rin MinamiDepartment of Neuropsychiatry, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.
Akito UnoDepartment of Neuropsychiatry, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.
Yutaka SawaiDepartment of Neuropsychiatry, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.
Ayako OkumaDepartment of Neuropsychiatry, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.
Satoshi YamaguchiResearch Center for Social Science and Medicine, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan.
Mitsuhiro MiyashitaResearch Center for Social Science and Medicine, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan.
Syudo YamasakiResearch Center for Social Science and Medicine, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan.
Shuntaro AndoDepartment of Neuropsychiatry, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.
Kiyoto KasaiDepartment of Neuropsychiatry, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan. kasaik-tky@umin.net.ORCID http://orcid.org/0000-0002-4443-4535

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWhile most adolescent self-harm (SH) is transient, a substantial minority of adolescents repeat and continue it, requiring intensive care. Although social environmental factors play an important role in adolescent psychological development, little is known about their role in the persistence of SH. Moreover, few studies have focused specifically on early adolescence, when SH often begins, hospital presentations after SH increase sharply, and many preventive programs typically commence. We aimed to identify social environmental risk factors at age 12 that predict the persistence of SH through ages 14 and 16 in a population-based cohort.

methodsWe used data from the Tokyo Teen Cohort study (N = 1501). The experience of SH was self-reported at three timepoints (12, 14 and 16 years of age), and categorized as none, transient (one timepoint), or persistent (≥ 2 timepoints). Potential risk factors were assessed at age 12, including family related factors, school and peer related factors, sociodemographic and developmental characteristics, and psychopathological experiences. Multivariable and multinomial logistic regression analyses were conducted to examine the associations of potential risk factors with transient and persistent SH.

resultsOf the 1501 participants 195 (13.0%) experienced transient SH and 53 (3.5%) experienced persistent SH. In fully adjusted models, maternal depressive/anxious symptoms and female sex predicted persistent SH (maternal depressive/anxious symptoms: OR 1.47, 95% CI 1.13-1.92, female: OR 4.74, 95% CI 2.18-10.29), whereas companionship with mother predicted lower likelihood (OR 0.50, 95% CI 0.28-0.89). Depressive symptoms and psychotic experiences (PEs) predicted both transient (depressive symptoms: OR 1.77, 95% CI 1.50-2.10, PEs: OR 1.57, 95% CI 1.36-1.82) and persistent SH (depressive symptoms: OR 2.03, 95% CI 1.55-2.66, PEs: OR 1.89, 95% CI 1.48-2.41).

conclusionsMaternal depressive/anxious symptoms were the risk factor of persistent SH and companionship with mother was protective against persistence even after adjustment for other factors. Care for maternal depressive/anxious symptoms and support for mother-child relationships would be required to prevent the persistence of SH, in addition to the care for children's depressive symptoms and PEs.

Indexed as

AdolescentBirth cohortLongitudinal studiesMother-child relationshipSelf-injurious behavior

Identifiers

PMID42251417
PMCPMC13573429

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.