Evidence map›Paper›PMID 42251326›Full record

ArticleBMC pregnancy and childbirth2026

Comparison of first trimester complete blood count parameters in missed abortion and healthy pregnant women: a retrospective case-control study.

Egemen Tural, Ayşe Deniz Ertürk Coşkun, Damla Demi̇r, Fisun Vural

Abstract readComparative Study
In one paragraph

Article in BMC pregnancy and childbirth, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Egemen TuralDepartment of Family Medicine, Cifteler Family Health Center, Eskisehir, Turkey. egementural1@gmail.com.ORCID http://orcid.org/0009-0007-4772-796X
Ayşe Deniz Ertürk CoşkunDepartment of Gynecology and Obstetrics, University of Health Sciences Haydarpasa Numune Training and Research Hospital, Istanbul, Turkey.ORCID http://orcid.org/0000-0003-0658-2366
Damla Demi̇rDepartment of Gynecology and Obstetrics, University of Health Sciences Haydarpasa Numune Training and Research Hospital, Istanbul, Turkey.ORCID http://orcid.org/0009-0002-6747-4596
Fisun VuralDepartment of Gynecology and Obstetrics, University of Health Sciences Haydarpasa Numune Training and Research Hospital, Istanbul, Turkey.ORCID http://orcid.org/0000-0002-1103-7357

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe aim of our study is to compare the markers and parameters obtained from complete blood count between patients diagnosed with missed abortion in the first trimester and a healthy pregnant control group. MATERIALS AND

methodsThis descriptive, retrospective, case-control study included 166 patients diagnosed with missed abortion according to ultrasound criteria, and an equal number of healthy pregnant controls, who visited the Gynecology and Obstetrics Clinic at a Training and Research Hospital from January 1, 2018, to July 1, 2023. Participants, with 5 to 14 weeks of gestation, were selected using simple random sampling. Data on age, gravida, parity, gestational week, and hemogram results were retrieved from medical records and compared. Statistical significance was set at p < 0.05.

resultsNo significant differences were observed between the case and control groups in terms of gravida, parity, age, or gestational week (p > 0.05). Likewise, comparisons of hemogram parameters and derived values, did not show statistically significant differences (p > 0.05). However, the multivariate logistic regression analysis revealed that each unit increase in lymphocyte count was linked to a 2.075 times higher risk of missed abortion (p = 0.040).

conclusionOur study found no significant differences in complete blood count parameters between the missed abortion and healthy pregnant groups. Although lymphocyte count was significant in the multivariate model, this association should be interpreted with caution, as complete blood count values were obtained at the time of diagnosis. Therefore, it does not indicate predictive value, and prospective studies are needed to determine whether lymphocyte count may serve as a pre-diagnostic marker.

Indexed as

Abortion, MissedPregnancy Trimester, FirstAdultBiomarkersBlood Cell CountCase-Control StudiesFemaleHumansLymphocyte CountPregnancyRetrospective StudiesBiomarkersAbortionLymphocytesMissedNeutrophilsPregnancy

Identifiers

PMID42251326
PMCPMC13459246

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