ArticleBMC neurology2026
Prognostic value of C-reactive protein to albumin ratio for in-hospital mortality in acute stroke patients.
Article in BMC neurology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThis study aimed to evaluate the prognostic significance of the C-reactive protein to albumin ratio (CAR) in predicting in-hospital mortality among patients presenting with acute stroke.
methodA total of 483 adult patients (≥ 18 years) consecutively hospitalized for stroke over a one-year period (July 2022 - July 2023) were analyzed retrospectively. Exclusion criteria include malignancy, autoimmune/rheumatological disorders, chronic infections, conditions affecting inflammation or protein status, including liver failure and nephrotic syndrome, cachexia (BMI < 18 kg/m²). Baseline demographics, comorbidities, and laboratory indices were recorded upon admission. The CAR was derived by dividing the C-reactive protein (CRP) level by the serum albumin level. Comparative analysis was conducted between the mortality and non-mortality groups. The independent prognostic value of CAR was determined via binary logistic regression model.
resultsSignificant differences were observed between the mortality and non-mortality groups regarding baseline laboratory parameters. Patients in the in-hospital mortality group exhibited significantly higher levels of glucose (p = 0.001), AST (p = 0.001), white blood cell (p = 0.001), CRP (< 0.001) and CAR (< 0.001) levels were found to be significantly higher. Conversely, hemoglobin levels were significantly lower in the mortality group (p = 0.031). As a result of Binary logistic regression analysis to find independent predictors of in-hospital mortality CAR (Exp(B) 95% CI = 1.047 (1.026-1.068) p < 0.001) and glucose (Exp(B) 95% CI = 1.006 (1.000-1.011) p = 0.048) were found as independent predictors. ROC curve analysis demonstrated that a CAR cutoff value of 1.06 predicted in-hospital mortality with 74% sensitivity and 65% specificity [AUC: 0.774, 95% CI: 0.686-0.862].
conclusionThe present study found a significant association between elevated CAR levels and early in-hospital mortality from all causes in patients with acute stroke. It also demonstrated that CAR may be an independent predictor of early in-hospital mortality from all causes in all patients hospitalized with acute stroke, both in the general ward and intensive care unit.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.