Evidence map›Paper›PMID 42251264›Full record

ArticleBMC surgery2026

Role of chest wall perforator flaps in reconstruction of upper inner breast defects.

Ahmed Orabi

Abstract read
In one paragraph

Article in BMC surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Ahmed OrabiBreast unit- Surgical Oncology Department, National Cancer Institute-Cairo University, Cairo, Egypt. Ahmed.orabi@nci.cu.edu.eg.ORCID http://orcid.org/0000-0001-8273-4945

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBreast-conserving surgery (BCS) is the standard treatment for early-stage breast cancer; however, defects in the upper inner quadrant (UIQ) remain a significant reconstructive challenge due to paucity of local tissue and heightened cosmetic sensitivity of this quadrant. Chest wall perforator flaps (CWPFs) have emerged as a reliable volume replacement option with minimal donor-site morbidity, yet data focusing specifically on their use in UIQ defects are limited.

methodsThis retrospective study included 20 female patients with UIQ breast tumors who underwent partial breast reconstruction using CWPFs between January 2022 and December 2023. Data regarding patient and tumor characteristics, flap type, operative details, and postoperative complications were collected. Aesthetic outcomes were objectively assessed using BCCT.core software (version 3.1), while patient-reported outcome measures (PROMs) were evaluated at 12 months postoperatively using the BREAST-Q questionnaire.

resultsThe mean patient age was 40.7 ± 5.0 years. The most commonly used flap was the anterior intercostal artery perforator (AICAP) flap (40%), followed by combined LICAP/LTAP flaps (25%). The mean operative time was 79.0 ± 7.5 min. Postoperative complications occurred in 20% of patients, including seroma (10%), wound infection (5%), and fat necrosis (5%), with no cases of major flap loss or positive surgical margins. According to BCCT assessment, excellent and good cosmetic outcomes were achieved in 95% of patients. PROMs demonstrated favorable outcomes, with mean scores of 73.4 ± 4.7 for physical well-being, 73.8 ± 4.2 for psychological well-being, and 70.1 ± 6.3 for satisfaction with the breast.

conclusionCWPFs were used for reconstruction of UIQ defects following breast-conserving surgery with acceptable postoperative complication rates and favorable cosmetic assessment in this retrospective cohort. These findings describe the surgical and aesthetic outcomes observed in this challenging breast quadrant. Further prospective studies with larger patient populations are needed to better define the role of CWPFs in UIQ reconstruction.

trial registrationRetrospectively registered after the approval of Baheya Ethical Committee, IRB no. 202,506,300,026.

Indexed as

Breast NeoplasmsMammaplastyMastectomy, SegmentalPerforator FlapThoracic WallAdultEstheticsFemaleHumansMiddle AgedPatient Reported Outcome MeasuresPatient SatisfactionPostoperative ComplicationsRetrospective StudiesBCCT.coreBreast-conserving surgeryChest wall perforator flapsOncoplastic breast surgeryPartial breast reconstructionPatient-reported outcomes.Upper inner quadrant

Identifiers

PMID42251264
PMCPMC13242130

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.