Evidence map›Paper›PMID 42251237›Full record

ReviewWorld journal of pediatrics : WJP2026

Effects of Helicobacter pylori infection on gastric mucosal microbiota.

Wei Zheng, Xiao-Rui He, Ji-Wei Zheng, Zhen-Ya Zhu, Di-Ya Ye, Xin-Yi Jia, Qian-Cheng Xu, Mi-Zu Jiang

Abstract readReview
PubMed Publisher
In one paragraph

Review in World journal of pediatrics : WJP, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Wei ZhengDepartment of Gastroenterology, Children's Hospital, National Clinical Research Center for Children and Adolescents' Health and Diseases, National Children's Regional Medical Center, Zhejiang University School of Medicine, Hangzhou, 310052, China.
Xiao-Rui HePediatric Endoscopy Center and Gastrointestinal Laboratory, Children's Hospital, National Clinical Research Center for Children and Adolescents' Health and Diseases, National Children's Regional Medical Center, Zhejiang University School of Medicine, Hangzhou, 310052, China.
Ji-Wei ZhengPediatric Endoscopy Center and Gastrointestinal Laboratory, Children's Hospital, National Clinical Research Center for Children and Adolescents' Health and Diseases, National Children's Regional Medical Center, Zhejiang University School of Medicine, Hangzhou, 310052, China.
Zhen-Ya ZhuDepartment of Gastroenterology, Children's Hospital, National Clinical Research Center for Children and Adolescents' Health and Diseases, National Children's Regional Medical Center, Zhejiang University School of Medicine, Hangzhou, 310052, China.
Di-Ya YeDepartment of Gastroenterology, Children's Hospital, National Clinical Research Center for Children and Adolescents' Health and Diseases, National Children's Regional Medical Center, Zhejiang University School of Medicine, Hangzhou, 310052, China.
Xin-Yi JiaDepartment of Gastroenterology, Children's Hospital, National Clinical Research Center for Children and Adolescents' Health and Diseases, National Children's Regional Medical Center, Zhejiang University School of Medicine, Hangzhou, 310052, China.
Qian-Cheng XuPediatric Endoscopy Center and Gastrointestinal Laboratory, Children's Hospital, National Clinical Research Center for Children and Adolescents' Health and Diseases, National Children's Regional Medical Center, Zhejiang University School of Medicine, Hangzhou, 310052, China.
Mi-Zu JiangDepartment of Gastroenterology, Children's Hospital, National Clinical Research Center for Children and Adolescents' Health and Diseases, National Children's Regional Medical Center, Zhejiang University School of Medicine, Hangzhou, 310052, China. mizu@zju.edu.cn.ORCID http://orcid.org/0000-0003-4829-2041

Funding

Key Technologies Research and Development Program 2023YFC2706500Key Technologies Research and Development Program 2023YFC2706504
6 · The paper itself

Abstract

backgroundHelicobacter pylori (H. pylori) is a Gram-negative obligate pathogen that colonizes the human gastric environment. Its identification fundamentally altered the historical perception of the stomach as sterile, marking a pivotal shift in gastric microbial research. For 30 years, the dynamic interplay between this bacterium and the gastric lining has been a key research focus. DATA SOURCES: The development of next-generation sequencing and advanced bioinformatics has provided powerful, culture-independent tools for probing the intricate diversity of the gastric microbiome. Current investigations extensively cover microbe-microbe interactions within the stomach, the relationship between the resident microbiota and H. pylori, and the dialogue between the microbiome and the host.

resultsThis article reviews current evidence detailing how H. pylori infection reshapes the microbial community on the human gastric mucosa.

conclusionFuture research employing integrated multi-omics strategies is essential to unravel the long-term consequences of H. pylori on the mucosal ecosystem and host physiology.

Indexed as

Gastric MucosaGastrointestinal MicrobiomeHelicobacter InfectionsHelicobacter pyloriMicrobiotaHumansChildrenGastric mucosal microbiotaHelicobacter pyloriPediatrics

Identifiers

PMID42251237

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.