Evidence map›Paper›PMID 42251154›Full record

ArticleCommunications medicine2026

Development and validation of the lifetime sense of safety scale in Kenyan adults.

Karen Blackmon, Anne N Nyambura, Anne Gitere, Levi A Muyela, Catherine Bikeri, Kendi Muchungi, Catherine Ajalo, Litha M Musili, Dina Abdalla, Rachel Maina and 4 more

Abstract read
In one paragraph

Article in Communications medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Karen BlackmonAga Khan University, Brain and Mind Institute, Nairobi, Kenya. karen.e.blackmon@dartmouth.edu.ORCID http://orcid.org/0000-0002-2665-7807
Anne N NyamburaAga Khan University, Brain and Mind Institute, Nairobi, Kenya.
Anne GitereAga Khan University, Brain and Mind Institute, Nairobi, Kenya.
Levi A MuyelaAga Khan University, Brain and Mind Institute, Nairobi, Kenya.
Catherine BikeriAga Khan University, Brain and Mind Institute, Nairobi, Kenya.
Kendi MuchungiAga Khan University, Brain and Mind Institute, Nairobi, Kenya.
Catherine AjaloAga Khan University, Brain and Mind Institute, Nairobi, Kenya.
Litha M MusiliAga Khan University, Brain and Mind Institute, Nairobi, Kenya.
Dina AbdallaGeisel School of Medicine at Dartmouth, Hanover, New Hamsphire, United States of America.
Rachel MainaAga Khan University, Brain and Mind Institute, Nairobi, Kenya.ORCID http://orcid.org/0000-0002-6038-1357
Edna BosireAga Khan University, Brain and Mind Institute, Nairobi, Kenya.
Lukoye AtwoliAga Khan University, Brain and Mind Institute, Nairobi, Kenya.
Zul MeraliAga Khan University, Brain and Mind Institute, Nairobi, Kenya.ORCID http://orcid.org/0000-0002-6360-7913
Chinedu Udeh-MomohAga Khan University, Brain and Mind Institute, Nairobi, Kenya.

Funding

Scalable Technologies for the Assessment and Rescue of Brain Health: Brain-STARTU01AG097744 · NIA · AGA KHAN UNIVERSITY (KENYA) · PI Karen Blackmon, Zul Merali · 2025 to 2026
$887k
NIA NIH HHS U01 AG097744Wellcome Trust
6 · The paper itself

Abstract

backgroundSafety supports psychological wellbeing and potentially shapes brain aging yet existing scales overlook cumulative lifespan safety experiences.

methodsTo address this gap, we developed and validated the Lifetime Sense of Safety (LSS) scale in Kenyan adults. The LSS uses visual analog scaling with a red-to-green color gradient to retrospectively rate felt safety across life stages and settings. We evaluated scale psychometrics and associations with social determinants of health and indicators of brain health.

resultsThe LSS shows adequate internal consistency and test-retest reliability, with two distinct but correlated factors representing childhood and adulthood safety. Women and individuals experiencing poverty report lower lifetime safety. Total LSS scores correlate negatively with stress and anxiety and positively with resilience and memory.

conclusionsThe LSS is a psychometrically valid tool for evaluating cumulative lifespan safety in Kenyan adults. Longitudinal studies combining the LSS with neuroendocrine, inflammatory, and neuroimaging measures could identify mechanisms linking safety to brain health.

Identifiers

PMID42251154
PMCPMC13575095

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.