ArticleInternal medicine journal2026
Comparing clinical manifestations, treatment strategies and outcomes of Staphylococcus lugdunensis bacteraemia versus Staphylococcus aureus bacteraemia - a retrospective cohort study.
Article in Internal medicine journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundStaphylococcus lugdunensis is a coagulase-negative Staphylococcus that has been increasingly recognised as a significant pathogen capable of causing invasive infections similar to Staphylococcus aureus. Data comparing the clinical manifestations and outcomes of S. lugdunensis bacteraemia to S. aureus bacteraemia remain limited. This article seeks to compare the two diseases in order to better understand the clinical course of S. lugdunensis bacteraemia.
aimsThis study aims to compare the clinical course, management strategies, outcomes and complications of S. lugdunensis and S. aureus bacteraemia in order to better characterise S. lugdunensis bacteraemia.
methodsWe conducted a retrospective cohort study of 57 patients with S. lugdunensis bacteraemia and 66 matched patients with S. aureus bacteraemia across a metropolitan health service in Melbourne, Australia, between 2012 and 2024. Patient demographics, clinical features, biochemical markers, management strategies and outcomes were compared.
resultsBaseline demographics and comorbidities were similar between the groups. S. lugdunensis was more frequently isolated in polymicrobial cultures compared to S. aureus (14/57 vs 2/66) and was more frequently viewed as a contaminant by treating clinicians (12/57 vs 1/66). S. aureus bacteraemia was associated with longer duration of bacteraemia, and more frequent osteoarticular and spinal epidural infections. However, rates of infective endocarditis were similar between the two groups (9/57 vs 15/66), and inpatient and 90-day mortality outcomes were comparable.
conclusionOur findings support the idea that S. lugdunensis bacteraemia should be approached with similar clinical vigilance as S. aureus, given comparable mortality and potential for serious complications, namely infective endocarditis. Improved clinician awareness is needed to reduce misclassification of S. lugdunensis as contaminants to allow for timely diagnosis and management.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.