Evidence map›Paper›PMID 42250187›Full record

ReviewClinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico2026

Is tattooing associated with an increased risk of cancer? A systematic review and meta-analysis.

Gabriel Caruso Novaes Tudella, Maria Luiza Rodrigues Defante, Pedro Sandes Pereira, Giovana Menegucci, Augusto Utida Klostermann, João Vitor Andrade Fernandes, Eduarda Lima Ornelas Pinto, Ocílio Ribeiro Gonçalves, António Balele Kanda João, Lília Maria Lima de Oliveira

Abstract readReview
PubMed Publisher
In one paragraph

Review in Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Gabriel Caruso Novaes TudellaDepartment of Medicine, Federal University of Santa Maria, Santa Maria, Brazil. tudellagabriel@gmail.com.ORCID http://orcid.org/0009-0001-4140-6045
Maria Luiza Rodrigues DefanteDepartment of Medicine, Redentor University Center, Itaperuna, Brazil.
Pedro Sandes PereiraDepartment of Medicine, Bahiana School of Medicine and Public Health, Salvador, Brazil.
Giovana MenegucciDepartment of Medicine, Federal University of Santa Maria, Santa Maria, Brazil.
Augusto Utida KlostermannDepartment of Medicine, Federal University of Santa Maria, Santa Maria, Brazil.
João Vitor Andrade FernandesMedical Sciences Center, Federal University of Paraíba, João Pessoa, Brazil.
Eduarda Lima Ornelas PintoDepartment of Medicine, Centro Universitário de Belo Horizonte (UniBH), Belo Horizonte, Brazil.
Ocílio Ribeiro GonçalvesDepartment of Medicine, Federal University of Piauí, Teresina, Brazil.
António Balele Kanda JoãoInstitute of Health Sciences, Agostinho Neto University, Luanda, Angola.
Lília Maria Lima de OliveiraPrinciples and Practice of Clinical Research (PPCR), Postgraduate Program, Harvard T. H. Chan School of Public Health, Boston, MA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTattoo inks may contain carcinogenic compounds, and pigment migration to lymphatic tissues raises concerns regarding potential cancer risk. Epidemiological evidence remains inconclusive.

objectivesTo assess the association between tattoo exposure and the incidence of skin cancer and hematological malignancies.

methodsPubMed, Embase, and the Cochrane Library were searched from inception to January 2026 for cohort and case-control studies comparing cancer incidence in tattooed versus non-tattooed adults. Random-effects meta-analyses using restricted maximum-likelihood estimators were performed to pool odds ratios (ORs) with 95% confidence intervals (CIs). Heterogeneity was quantified using I

resultsSeven observational studies including 140,841 participants were analyzed. Tattoo exposure was not associated with overall skin cancer (OR 0.92; 95%CI 0.83-1.04; I

conclusionsTattoo exposure was not associated with increased skin cancer risk and showed no significant association with hematological malignancies in primary analyses. A significant association emerged only after sensitivity analysis, warranting cautious interpretation and further prospective investigation.

Indexed as

LymphomaMelanomaMeta-analysisNeoplasmTattooing

Identifiers

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.