Evidence map›Paper›PMID 42250164›Full record

ArticleGastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association2026

Clinical outcomes of endoscopic resection for remnant gastric cancer: a multicenter prospective cohort study.

Yosuke Toya, Takayuki Matsumoto, Haruhisa Suzuki, Kohei Takizawa, Toshiaki Hirasawa, Yoji Takeuchi, Kenji Ishido, Shu Hoteya, Tomonori Yano, Shinji Tanaka and 21 more

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

31 authors.

Yosuke ToyaDivision of Gastroenterology and Hepatology, Department of Internal Medicine, School of Medicine, Iwate Medical University, Iwate, Japan.
Takayuki MatsumotoDivision of Gastroenterology and Hepatology, Department of Internal Medicine, School of Medicine, Iwate Medical University, Iwate, Japan.
Haruhisa SuzukiDivision of Gastroenterology and Hepatology, Department of Medicine, Nihon University School of Medicine, Tokyo, Japan. suzuki.haruhisa@nihon-u.ac.jp.
Kohei TakizawaDivision of Endoscopy, Shizuoka Cancer Center, Shizuoka, Japan.
Toshiaki HirasawaDepartment of Gastroenterology, Cancer Institute Hospital, Tokyo, Japan.
Yoji TakeuchiDepartment of Gastrointestinal Oncology, Osaka International Cancer Institute, Osaka, Japan.
Kenji IshidoDepartment of Gastroenterology, Kitasato University School of Medicine, Sagamihara, Japan.
Shu HoteyaDepartment of Gastroenterology, Toranomon Hospital, Tokyo, Japan.
Tomonori YanoDepartment of Gastroenterology and Endoscopy, National Cancer Center Hospital East, Kashiwa, Japan.
Shinji TanakaDepartment of Gastroenterology, JA Onomichi General Hospital, Onomichi-City, Hiroshima, Japan.
Masahiro NakagawaDepartment of Endoscopy, Hiroshima City Hiroshima Citizens Hospital, Hiroshima, Japan.
Tetsuya YoshizakiDivision of Gastroenterology, Department of Internal Medicine, Kobe University Graduate School of Medicine, Kobe, Japan.
Naohiro YoshidaDepartment of Gastroenterology, Ishikawa Prefectural Central Hospital, Kanazawa, Japan.
Kingo HirasawaDivision of Endoscopy, Yokohama City University Medical Center, Yokohama, Japan.
Mitsuru MatsudaDepartment of Gastroenterology, Toyama Prefectural Central Hospital, Toyama, Japan.
Hironori YamamotoDepartment of Medicine, Division of Gastroenterology, Jichi Medical University, Tochigi, Japan.
Tetsuya SumiyoshiDepartment of Gastroenterology, Tonan Hospital, Sapporo, Japan.
Shinji KitamuraDepartment of Gastroenterology and Oncology, Tokushima University Graduate School of Biomedical Sciences, Tokushima, Japan.
Hisao TanakaChiyominomori General Medicine and Gastroenterology Clinic, Tottori, Japan.
Ryo ShimodaDepartment of Endoscopic Diagnostics and Therapeutics, Saga University Hospital, Saga, Japan.
Yumi MashimoDepartment of Gastroenterology, Chofu Touzan Hospital, Tokyo, Japan.
Ryutaro MorizonoDepartment of Surgery, Kin-I-Kyo Central Hospital, Sapporo, Japan.
Kazutoshi FukaseDepartment of Gastroenterology, Yamagata Prefectural Central Hospital, Yamagata, Japan.
Taichi ShimazuDivision of Behavioral Sciences, National Cancer Center Institute for Cancer Control, National Cancer Center, Tokyo, Japan.
Hiroyuki OnoDivision of Endoscopy, Shizuoka Cancer Center, Shizuoka, Japan.
Satoshi TanabeDepartment of Gastroenterology, Ebina General Hospital, Ebina, Japan.
Hitoshi KondoDepartment of Gastroenterology, Tonan Hospital, Sapporo, Japan.
Hiroyasu IishiDepartment of Gastrointestinal Oncology, Osaka International Cancer Institute, Osaka, Japan.
Motoki NinomiyaDigestive Disease Center, Yuuai Medical Center, Okinawa, Japan.
Ichiro OdaEndoscopy Division, National Cancer Center Hospital, Tokyo, Japan.
J-WEB/EGC group

Funding

Daiwa Securities Health Foundation H24-16Ministry of Health, Labour and Welfare 25-A-12Ministry of Health, Labour and Welfare 28-K-1Ministry of Health, Labour and Welfare 29-A-13Ministry of Health, Labour and Welfare H21-022
6 · The paper itself

Abstract

backgroundWhile the incidence of early-stage remnant gastric cancer (RGC) is increasing, evidence for the validity of endoscopic resection (ER) for RGC remains limited. We aimed to clarify outcomes of ER for RGC.

methodsThis is the second analysis of a nationwide prospective cohort study of ER for early gastric cancer (EGC) at 41 Japanese centers from July 2010 to June 2012. We compared short-term and long-term outcomes of 355 patients with 369 RGCs and 8460 patients with 9394 primary EGCs in the naïve stomach. We calculated 5-year overall survival (OS) and disease-specific survival (DSS) rates. Hazard ratios (HRs) for all-cause mortality were estimated using a Cox regression model; patients with curatively resected primary EGC were the reference group.

resultsFor RGCs and primary EGCs, median procedure times were 87 and 77 min (p < 0.001); en-bloc resection rates were 96.7 and 99.5% (p < 0.001); R0 resection rates were 83.5 and 93.3% (p < 0.001); intraoperative perforation rates were 4.2 and 1.9% (p = 0.002); and delayed perforation rates were 1.1 and 0.3% (p = 0.018), respectively. 5-year OS (83.1% vs 89.5%, p < 0.001) and DSS (98.5% vs 99.6%, p = 0.002) were lower in RGC cases than primary EGC cases. HRs for all-cause mortality against curatively resected primary EGC were 1.19 (95% CI 0.85-1.66) for curatively resected RGC, 1.37 (1.12-1.60) for non-curatively resected primary EGC, and 1.87 (1.21-2.90) for non-curatively resected RGC.

conclusionsAlthough ER for RGC showed slightly inferior short-term outcomes to ER for primary EGC, long-term outcomes were comparable under the curative resection.

Indexed as

GastrectomyGastric StumpGastroscopyStomach NeoplasmsAgedAged, 80 and overFemaleFollow-Up StudiesHumansMaleMiddle AgedPrognosisProspective StudiesSurvival RateTreatment OutcomeEndoscopic mucosal resectionGastric stumpPrognosisStomach neoplasms

Identifiers

PMID42250164

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.