Evidence map›Paper›PMID 42249999›Full record

SynthesisEuropean journal of orthopaedic surgery & traumatology : orthopedie traumatologie2026

Posterior-only versus combined anterior-posterior approaches for thoracolumbar burst fractures: a meta-analysis.

Marc Boutros, Guy Awad, Shaza Hammad, Reina Khatib, Zina Smadi, Chahine Assi

Abstract readComparative StudyMeta-Analysis
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Synthesis in European journal of orthopaedic surgery & traumatology : orthopedie traumatologie, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

6 authors.

Marc BoutrosFaculty of Medicine, Saint Joseph University, Beirut, Lebanon. marceboutros@gmail.com.
Guy AwadFaculty of Medicine, Saint Joseph University, Beirut, Lebanon.
Shaza HammadFaculty of Medicine, Saint Joseph University, Beirut, Lebanon.
Reina KhatibFaculty of Medicine, Saint Joseph University, Beirut, Lebanon.
Zina SmadiDepartment of Pediatric Orthopedics, Texas Children's Hospital, Houston, USA.
Chahine AssiDepartment of Orthopaedic Surgery, University Medical Center Rizk Hospital, Beirut, Lebanon.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThoracolumbar burst fractures are among the most common spinal injuries, and optimal surgical management remains controversial. Evidence comparing posterior-only and combined anterior-posterior fixation strategies remains inconsistent.

methodsA systematic search of PubMed, Scopus, Cochrane Library, and Google Scholar was conducted up to November 2025 to identify comparative studies evaluating posterior-only versus combined anterior-posterior fixation for thoracolumbar burst fractures. Nineteen studies (predominantly retrospective; 15 non-randomized and 4 randomized) met inclusion criteria, comprising 1553 patients. Outcomes included perioperative parameters (operative time, blood loss, hospital stay), neurological recovery (Frankel scores), pain and functional outcomes (VAS, ODI, RMDQ, return-to-work rates), radiological parameters (Cobb angle correction, canal compromise recovery), and complication rates (infection, instrumentation failure, pulmonary complications).

resultsPosterior-only fixation was associated with significantly reduced blood loss (MD = - 438.21 mL, p < 0.001), shorter operative time (MD = - 121.66 min, p < 0.001), and shorter hospital stay (MD = - 5.62 days, p < 0.001), although heterogeneity was substantial for perioperative outcomes. Pulmonary complications were also lower in the posterior group (RR = 0.16, p = 0.009). No significant differences were found between approaches in neurological improvement, pain scores, functional recovery, radiological correction, infection rates, or instrumentation failure.

conclusionsBoth posterior-only and combined anterior-posterior fixation show broadly similar neurological, radiological, and functional outcomes in thoracolumbar burst fractures. Posterior-only fixation was associated with perioperative advantages and a lower risk of pulmonary complications. Surgical decision-making should therefore be individualized based on fracture morphology, neurological status, and patient-specific factors, particularly given that most included evidence remains observational.

Indexed as

Fracture Fixation, InternalLumbar VertebraeSpinal FracturesThoracic VertebraeBlood Loss, SurgicalHumansLength of StayOperative TimePostoperative ComplicationsTreatment OutcomeAnterior–posterior fixationCombined approachPosterior fixationSpinal surgeryThoracolumbar burst fracture

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.