Evidence map›Paper›PMID 42249927›Full record

Trial reportEuropean journal of applied physiology2026

Cadence effects on cardiorespiratory and muscular responses during eccentric cycling.

Marc-Étienne Villeneuve, Jonathan Tremblay, Valérie Julian, Emmanuel Coudeyre, Frédéric Costes, Ruddy Richard

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in European journal of applied physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Marc-Étienne VilleneuveÉcole de kinésiologie et des sciences de l'activité physique, Faculté de Médecine, Université de Montréal, Succursale Centre-ville, C.P. 6128, Montreal, Québec, H3C 3J7, Canada.ORCID http://orcid.org/0009-0001-6634-1938
Jonathan TremblayÉcole de kinésiologie et des sciences de l'activité physique, Faculté de Médecine, Université de Montréal, Succursale Centre-ville, C.P. 6128, Montreal, Québec, H3C 3J7, Canada. jonathan.tremblay@umontreal.ca.
Valérie JulianDépartement de médecine du sport et des explorations fonctionnelles, CHU Gabriel-Montpied, Université Clermont Auvergne, Clermont-Ferrand, France.
Emmanuel CoudeyreDépartement de Médecine Physique et Réadaptation, CHU Gabriel-Montpied, Université Clermont Auvergne, Clermont-Ferrand, France.
Frédéric CostesDépartement de médecine du sport et des explorations fonctionnelles, CHU Gabriel-Montpied, Université Clermont Auvergne, Clermont-Ferrand, France.
Ruddy RichardÉcole de kinésiologie et des sciences de l'activité physique, Faculté de Médecine, Université de Montréal, Succursale Centre-ville, C.P. 6128, Montreal, Québec, H3C 3J7, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeEccentric cycling (ECC) enables high mechanical power output at a low metabolic cost, yet the influence of cadence on cardiorespiratory and neuromuscular responses during ECC remains poorly defined. This study examined the interactive effects of cadence and power output on metabolic, cardiovascular, and muscle activation responses during ECC.

methodsFifteen healthy men performed randomized incremental ECC trials at 50 and 80 rpm, with successive 4-min stages at 80, 200, and 320 W. Oxygen uptake [Formula: see text], gross mechanical efficiency (GME), cardiac output [Formula: see text], heart rate (HR), stroke volume (Qs), arteriovenous O

resultsA significant cadence × power interaction was observed for [Formula: see text] (p = 0.006). [Formula: see text] was lower at 80 rpm than at 50 rpm at 200 W (- 0.116 L·min

conclusionDuring eccentric cycling, higher cadence reduces oxygen uptake and vastus lateralis activation at moderate to high power outputs, without altering fundamental cardiovascular-metabolic coupling. These findings indicate that cadence selection modulates the metabolic and neuromuscular cost of eccentric work primarily through contraction mechanics, supporting the use of higher cadences to optimize eccentric cycling in both rehabilitation and performance settings.

Indexed as

BicyclingMuscle, SkeletalAdultCardiac OutputHealthy VolunteersHeart RateHumansMaleMuscle ContractionOxygen ConsumptionStroke VolumeYoung AdultArteriovenous oxygen differenceCardiac outputElectromyographyGross mechanical efficiencyOxygen uptake

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.