Trial reportWorld journal of urology2026
Does an anti-reflux ureteral stent offer real benefits for children after endoscopic surgery for upper urinary tract stones? A single-center randomized controlled trial.
Trial report in World journal of urology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06569173 (Comparison of the Drainage/Anti-reflux Effect and Stent-Related Symptoms Between Anti-Reflux Stents and Standard DJ Stents in Children With Urolithiasis), which is not on this map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Comparison of the Drainage/Anti-reflux Effect and Stent-Related Symptoms Between Anti-Reflux Stents and Standard DJ Stents in Children With Urolithiasis
Who cites it
0 citing papers in PubMed.
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Authors and funding
6 authors.
Funding
Abstract
objectiveTo determine whether anti-reflux ureteral stents improve postoperative stent-related symptoms and complications compared with conventional Double-J (DJ) stents in children undergoing ureteroscopic lithotripsy (URL) or retrograde intrarenal surgery (RIRS).
methodsChildren undergoing URL and RIRS were prospectively randomized in a 1:1 ratio by block randomization to receive either a 4.8-Fr anti-reflux stent or a 4.7-Fr conventional DJ stent. Postoperative symptoms were assessed 2 weeks after surgery using age-adapted versions of the pediatric ureteral stent symptom questionnaire (PUSSQ), with separate forms for toilet-trained and pre-toilet-trained children. Stone-free rates and stent-related complications were also evaluated. The trial was registered at ClinicalTrials.gov (NCT06569173).
resultsA total of 88 children were included. Baseline characteristics were comparable between the two groups in both strata. Among toilet-trained children, the incidence of flank pain was lower (P = 0.047) in the anti-reflux stent group than the conventional DJ stent group, but body pain scores (P = 0.031) and urinary symptom scores (P = 0.009) were higher in the anti-reflux stent group. In pre-toilet-trained children, body pain scores (P = 0.048) and urinary symptom scores (P = 0.040) were also significantly higher in the anti-reflux group. No significant between-group differences were observed in other body pain manifestations, stent migration, stent extrusion, steinstrasse, or other complications. Stone-free rates were comparable between groups.
conclusionAnti-reflux stents reduced flank pain in toilet-trained children but were associated with more pronounced LUTS and body pain in both toilet-trained and pre-toilet-trained children. Overall, the anti-reflux ureteral stents may not confer a definitive clinical benefit in children after URL or RIRS.
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