ArticleJACC. Case reports2026
Rescuing Acute Myocardial Infarction-Related Left Ventricular Rupture and Severe Mitral Regurgitation With ECMO.
Article in JACC. Case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Caution Before Redefining Management of Postinfarction Mechanical Complications.JACC. Case reports · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundVentricular free wall rupture (VFWR) and acute mitral regurgitation (MR) are life-threatening complications of acute myocardial infarction (AMI). Although surgical intervention is standard, alternatives are needed for those unfit for immediate operation. CASE SUMMARY: An 81-year-old woman developed a VFWR with tamponade and severe MR after inferior AMI. Conservative management with pericardiocentesis and extracorporeal membrane oxygenation (ECMO) stabilized her hemodynamics, allowing spontaneous VFWR sealing. After ECMO weaning, refractory heart failure due to severe MR prompted transcatheter edge-to-edge repair (TEER). TEER successfully reduced MR from 4+ to 1+, enabling recovery to NYHA functional class I. DISCUSSION: This case demonstrates that a small VFWR may heal conservatively under ECMO support, challenging the dogma of mandatory emergency surgery. TEER after stabilization is feasible for post-AMI MR in high-risk patients. TAKE-HOME MESSAGES: Conservative management with ECMO support can be a viable option for small VFWR in selected high-risk patients. TEER is a valuable therapeutic alternative for severe MR in patients with concomitant VFWR or those at prohibitive surgical risk.
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Registered trials
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