Evidence map›Paper›PMID 42249758›Full record

ArticlePsycho-oncology2026

Fear of Progression in Pediatric Cancer Patients and Their Parents: Trajectories, Prevalence, and Correlates Across Acute Treatment and Follow-Up Care.

Jessy Herrmann, Kristina Herzog, Julia Martini, Anja Santel, Leonard Konstantin Kulisch, Jörn-Sven Kühl, Florian Schepper

Abstract read
In one paragraph

Article in Psycho-oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Trial
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jessy HerrmannDepartment of Pediatric Oncology, Haematology and Haemostaseology, Leipzig University, Leipzig, Germany.ORCID https://orcid.org/0000-0003-4286-7414
Kristina HerzogDepartment of Paediatric Oncology and Haematology, University Hospital Carl Gustav Carus Dresden, Dresden, Germany.ORCID https://orcid.org/0000-0003-2902-0171
Julia MartiniDepartment of Psychiatry and Psychotherapy, Faculty of Medicine of the Technische Universität Dresden, Dresden, Germany.ORCID https://orcid.org/0000-0002-9524-8257
Anja SantelRegistered Association for parents of children with cancer Leipzig, Leipzig, Germany.
Leonard Konstantin KulischMental Health Research and Treatment Centre (FBZ), Faculty of Psychology, Ruhr-University Bochum and German Center for Mental Health (DZPG), Bochum, Germany.ORCID https://orcid.org/0000-0002-9754-0411
Jörn-Sven KühlDepartment of Pediatric Oncology, Haematology and Haemostaseology, Leipzig University, Leipzig, Germany.ORCID https://orcid.org/0000-0002-1739-1090
Florian SchepperDepartment of Pediatric Oncology, Haematology and Haemostaseology, Leipzig University, Leipzig, Germany.ORCID https://orcid.org/0000-0002-7656-5556

Funding

Deutsche Krebshilfe DKH-70112444Deutsche Krebshilfe DKH-70112467
6 · The paper itself

Abstract

purposeFear of progression (FoP) represents a significant psychological burden for pediatric cancer patients and their parents. This study investigates FoP levels across acute treatment (AcT) and follow-up care (FuC) and examines trajectories over time, associated sociodemographic factors, and parent-child associations. It also proposes clinically relevant thresholds for psychosocial care.

methodsA total of 171 patient-parent dyads participated in a cross-sectional and longitudinal study. Children aged 7-18 and one parent per child completed the Fear of Progression Questionnaire-Short Form (FoP-Q-SF). Data were collected during AcT (two time points) and FuC. Statistical analyses included nonparametric tests and correlation analyses.

resultsFoP levels were significantly lower during FuC compared to AcT for both children and parents, and parental FoP decreased over the 1-year follow-up period. Parents consistently showed higher FoP than their children, and a significant parent-child correlation emerged in FuC. FoP was higher in girls and was positively associated with child age and negatively associated with parent age. Using suggested thresholds, 57.8% of parents showed dysfunctional FoP. Among children, 45.2% reported low, 40% moderate, and 14.8% high FoP.

conclusionAlthough levels of FoP are lower in FuC than in AcT, they remain a prevalent burden-particularly for younger parents, older children, and girls. The observed parent-child associations highlight the need for family-oriented psychosocial care. A proposed three-stage cut-off (low, moderate, high FoP) may guide clinical decision-making and support tailored treatment strategies. Routine screening and preventive approaches are recommended to mitigate FoP and its potential intergenerational transmission.

trial registrationThe study has been pre-registered at the German Clinical Trials Register (DRKS 00022034, registered 29

Indexed as

Disease ProgressionFearNeoplasmsParentsAdolescentAdultChildCross-Sectional StudiesFemaleFollow-Up StudiesHumansLongitudinal StudiesMaleParent-Child RelationsPrevalenceSurveys and Questionnairesfamily‐centered carefear of progressionlongitudinal studyparental distresspediatric oncologypsychosocial burden

Identifiers

PMID42249758
PMCPMC13242078

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.