ArticlePediatric transplantation2026
Early Living Donor Liver Transplant Is Associated With Improved Graft- and Patient-Survival Outcomes in Children With Biliary Atresia.
Article in Pediatric transplantation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Early Living Donor Liver Transplantation in Biliary Atresia: The Next Challenge Is Equity.Pediatric transplantation · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionBiliary atresia (BA) is the most common indication for pediatric liver transplantation. Pediatric end-stage liver disease (PELD) scores primarily determine deceased donor liver transplant (DDLT) waitlist priority. Due to persistent donor supply-demand mismatch, children typically have advanced disease and high PELD scores at the time of DDLT. Proactive living donor liver transplant (LDLT) may facilitate transplantation before critical illness. We hypothesized that early, low PELD, LDLT is associated with improved graft and patient survival in children with BA.
methodsWe retrospectively reviewed children undergoing liver transplantation for BA in the SRTR database, comparing DDLT to LDLT, stratified by PELD. Early transplant was defined as transplant with a PELD ≤ 12. Four groups were analyzed: low PELD LDLT, low PELD DDLT, high PELD LDLT, and high PELD DDLT. Kaplan-Meier and Cox-proportional hazards analyses evaluated patient- and graft-survival.
results4733 children meeting inclusion criteria were included (n = 249 Low PELD LDLT, n = 1152 Low PELD DDLT, n = 708 High PELD LDLT, n = 2624 High PELD DDLT). Prior to transplant, Low PELD LDLT recipients had lower INR and bilirubin levels, and required less life support (p < 0.01). Kaplan-Meier analyses showed the highest 5-year graft and patient survival in the Low PELD LDLT (p < 0.01). Cox modeling revealed an independent association between low PELD LDLT and decreased graft loss (adjusted HR 0.45, p < 0.01) and mortality (adjusted HR 0.43, p = 0.03).
conclusionsA proactive approach to LDLT in children with BA is associated with improved long-term graft and patient survival. Low PELD LDLT should be considered to increase early transplant access for children with BA.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.