ArticleJournal of oral rehabilitation2026
Examining Laterality in Masticatory Myofascial Pain.
Article in Journal of oral rehabilitation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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6 authors.
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Abstract
objectiveTo characterize unilateral and bilateral masticatory myofascial pain (MMP) in a clinical cohort. MATERIALS AND
methodsPatients meeting criteria for MMP according to the Research Diagnostic Criteria for Temporomandibular Disorders were recruited over a 2-year period. Demographic and clinical date were recorded. Data for unilateral and bilateral pain were analysed using Mann-Whitney U, Kruskal-Wallis H, and Fisher's Exact tests. Variables showing a p < 0.2 were entered into a binary logistic regression model, with pain laterality as the dependent variable.
resultsPatients with unilateral pain exhibited muscle tenderness both ipsilaterally and bilaterally, and patients with bilateral pain likewise demonstrated tenderness bilaterally and unilaterally. Unilateral pain was significantly associated with pain-related awakening (p = 0.03), nausea (p = 0.01), and primary pain (p = 0.01). These associations were confirmed in the regression analysis. Patients with unilateral and bilateral pain were similar in demographic characteristics.
conclusionsUnilateral and bilateral masticatory muscle pain differ in three clinical domains. Unilateral pain is significantly associated with pain-related awakening, primary pain, and nausea. The significance of these findings needs further study in a larger cohort. Additionally, the potential relationship between unilateral/bilateral MMP and headache warrants further investigation.
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