Evidence map›Paper›PMID 42249516›Full record

ReviewBreast cancer research : BCR2026

Intraoperative measurement of breast-conserving surgery margins: surgical application.

Wei-Ling Chen, Wan-Ling Liu, Cui-Ping Guo, Yuan-Yuan Zhu, Zi-He Ming, Yu-Tong Fang, Wan-Di Zhang, Rong Chen, Jun-Dong Wu, Jie Li and 2 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Breast cancer research : BCR, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Wei-Ling Chen *Department of Breast and Thyroid Surgery, Xiang' an Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, Fujian, China.
Wan-Ling Liu *Department of Nuclear Medicine and Molecular Imaging, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Cui-Ping GuoDepartment of Breast Center, Cancer Hospital of Shantou University Medical College, Shantou, Guangdong, China.
Yuan-Yuan ZhuDepartment of Breast and Thyroid Surgery, Xiang' an Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, Fujian, China.
Zi-He MingDepartment of Nuclear Medicine and Molecular Imaging, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Yu-Tong FangDepartment of Breast Center, Cancer Hospital of Shantou University Medical College, Shantou, Guangdong, China.
Wan-Di ZhangDepartment of Breast Center, Cancer Hospital of Shantou University Medical College, Shantou, Guangdong, China.
Rong ChenDepartment of Breast Center, Cancer Hospital of Shantou University Medical College, Shantou, Guangdong, China.
Jun-Dong WuDepartment of Breast Center, Cancer Hospital of Shantou University Medical College, Shantou, Guangdong, China. wujun-dong@163.com.
Jie LiDepartment of Breast Center, Cancer Hospital of Shantou University Medical College, Shantou, Guangdong, China. Lijie2958@gwcmc.org.
Christobel M SaundersDepartment of Surgery, Melbourne University Medical School, 155 Barry Street, Carlton, VIC, 3053, Australia. christobel.saunders@unimelb.edu.au.
Yong-Qu ZhangDepartment of Breast Center, Cancer Hospital of Shantou University Medical College, Shantou, Guangdong, China. zhangyq@stu.edu.cn.

Funding

Guangdong Basic and Applied Basic Research Foundation 2024A1515011271the National Natural Science Foundation of China 81602345
6 · The paper itself

Abstract

Breast-conserving surgery (BCS) is an effective treatment for early-stage cancer, provided that there is "no ink on tumor" reported in the excised breast specimen. However, approximately 15-35% of patients require additional surgery due to the presence of malignant cells at the surgical margin. In this review, we examine the available data on margin status in breast cancer and compare the advantages and disadvantages of different approaches in BCS margin evaluation. Of note, there are numerous concerns regarding traditional methods for assessing margins, and emerging technological approaches are gaining attention. The use of new imaging devices and molecular probes for surgical navigation represents a significant research direction for the future. Ultimately, collaboration between scientists from various fields is essential in reducing positive rates at breast-conserving margins and improving re-excision rates with associated poor outcomes, and ultimately decreasing recurrence.

Indexed as

Breast NeoplasmsMargins of ExcisionMastectomy, SegmentalFemaleHumansNeoplasm Recurrence, LocalBreast-conserving surgeryIntraoperative measuresMargin assessment

Identifiers

PMID42249516
PMCPMC13471554

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.