ArticleTropical medicine and health2026
Appendicitis burden in Africa, 2010-2023: temporal trends, pandemic-era deviations, and projections to 2030.
Article in Tropical medicine and health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionAppendicitis is a common abdominal surgical emergency, but continent-wide evidence on its burden and trends in Africa is limited. We assessed the burden, trends, geographic heterogeneity, demographic drivers, pandemic-era deviations, and future projections of appendicitis across Africa.
methodsWe conducted a population-level secondary analysis using Global Burden of Disease 2023 estimates for the African Union and 54 African countries from 2010 to 2023. We examined incidence, prevalence, deaths, and disability-adjusted life-years (DALYs) as absolute numbers and age-standardized rates (ASRs). Trends, drivers of change, pandemic-era deviations, and projections to 2030 were evaluated.
resultsFrom 2010 to 2023, appendicitis burden increased across Africa: incident cases rose from 2.45 to 3.73 million, prevalent cases from 92,805 to 141,711, deaths from 3,240 to 3,984, and DALYs from 182,086 to 226,592. Age-standardized incidence and prevalence increased modestly, whereas age-standardized death and DALY rates declined. Higher nonfatal burden was concentrated in parts of southern and western Africa, while fatal and disability burden remained highest in eastern Africa. Population growth was the main driver of increasing burden. During 2020-2023, incidence and prevalence exceeded expected levels, whereas deaths and DALYs were lower than expected. By 2030, incidence and prevalence are projected to increase in most countries, while death and DALY rates are projected to decline in most settings.
conclusionsAppendicitis burden in Africa increased substantially between 2010 and 2023, largely driven by demographic expansion. Persistent geographic inequalities highlight the need to strengthen timely diagnosis, referral, and emergency surgical care.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.