ArticleParasites & vectors2026
Closing the gap on gapeworm: experimental infection of Mammomonogamus ierei in domestic cats.
Article in Parasites & vectors, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
backgroundMammomonogamus ierei is a nasal nematode of domestic cats, for which the life cycle and route of infection have remained unknown. Experimental oral infections have historically failed, leading to speculation regarding the involvement of an intermediate host and uncertainty about transmission pathways. The aim of this study was to determine the route of infection of M. ierei in domestic cats.
methodsTwenty kittens (6-12 weeks old) were exposed to infective third-stage larvae (L3) via six routes: per os (n = 3), oral mucosa (n = 3), nasal mucosa (n = 3), subcutaneous (n = 3), percutaneous (abdominal region) (n = 2), external auditory canal (n = 2), and an unexposed control group (n = 4). Kittens were randomized across litters to minimize litter-associated effects and monitored using serial fecal examinations for 70 days post-inoculation to assess establishment of infection and egg shedding.
resultsMotile L3 developed within 9 days in culture and exhibited morphometric characteristics consistent with previous descriptions. Two of 20 kittens developed patent M. ierei infections, first shedding eggs 48-51 days post-inoculation. Both infected animals belonged to the subcutaneous inoculation group, whereas no infections resulted from other inoculation routes. Mild, transient respiratory signs were observed in some kittens, including one prior to patency.
conclusionsThese findings demonstrate, for the first time, a viable route of infection for M. ierei and provide the first experimental evidence of route of transmission for any species within the genus Mammomonogamus. The results suggest a direct life cycle, as infection was established in the absence of an intermediate host, but do not preclude the occurrence of paratenic hosts. Infection via subcutaneous exposure was successfully achieved; however, its relevance under natural conditions remains to be confirmed. This study advances the current understanding of Mammomonogamus biology and may have implications for parasite control and for transmission models of zoonotic species such as Mammomonogamus laryngeus.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.