Evidence map›Paper›PMID 42249342›Full record

ArticleBMC ophthalmology2026

The influence of pterygium size on corneal refractive properties and higher-order aberrations.

Jianqin Shen, Ying Chen, Yanghong Chen, Bingzhen Gou, Hongguang Cui

Abstract read
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Article in BMC ophthalmology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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5 authors.

Jianqin ShenDepartment of Ophthalmology, The First Affiliated Hospital, School of Medicine, Zhejiang University, Qingchun Road No.79, Hangzhou, 310003, P.R. China.
Ying ChenDepartment of Ophthalmology, The First Affiliated Hospital, School of Medicine, Zhejiang University, Qingchun Road No.79, Hangzhou, 310003, P.R. China.
Yanghong ChenDepartment of Ophthalmology, The First Affiliated Hospital, School of Medicine, Zhejiang University, Qingchun Road No.79, Hangzhou, 310003, P.R. China.
Bingzhen GouDepartment of Ophthalmology, The First Affiliated Hospital, School of Medicine, Zhejiang University, Qingchun Road No.79, Hangzhou, 310003, P.R. China.
Hongguang CuiDepartment of Ophthalmology, The First Affiliated Hospital, School of Medicine, Zhejiang University, Qingchun Road No.79, Hangzhou, 310003, P.R. China. 1189002@zju.edu.cn.ORCID http://orcid.org/0000-0001-7311-0188

Funding

Zhejiang Provincial Natural Science Foundation of China ZCLTGY24H1201
6 · The paper itself

Abstract

objectiveTo evaluate associations between pterygium size parameters and corneal refractive properties and higher-order aberrations (HOAs).

methodsIn 41 patients with unilateral pterygium, thickness, length, and width were measured by anterior segment optical coherence tomography(AS-OCT). Corneal refractive parameters, irregularity indices, and HOAs were assessed using Pentacam HR. Correlation analyses evaluated relationships between pterygium dimensions and corneal parameters.

resultsPterygium length and width significantly correlated with multiple corneal parameters in the 3-7 mm zone. Moderate correlations were found with K1 (length: |r| = 0.376-0.473; width: |r| = 0.361-0.415; all p < 0.05), and stronger correlations with corneal astigmatism (length: r = 0.582-0.642; width: r = 0.529-0.581; all p < 0.001) and irregularity indices (ISV, IVA, IHD) (length: r = 0.623-0.637; width: r = 0.566-0.596; all p < 0.001). Length positively correlated with total, third-, and fourth-order HOA RMS across the anterior and posterior surface, and entire cornea (r = 0.455-0.691, p < 0.05), primarily driven by vertical trefoil, vertical coma, and tetrafoil. Width also correlated with anterior and total corneal HOAs (r = 0.519 to 0.645, p < 0.05). Posterior surface correlations for width were weaker (r = 0.313 to 0.472, p < 0.05) but remained significant for total RMS, third-order RMS, and several specific aberrations.

conclusionPterygium length and width are key parameters associated with deteriorated corneal refractive status, irregularity, and HOAs. Width, being easily standardized, serves as a practical indicator for predicting pterygium-induced visual quality deterioration.

Indexed as

CorneaCorneal Wavefront AberrationPterygiumRefraction, OcularAdultAgedCorneal TopographyFemaleHumansMaleMiddle AgedTomography, Optical CoherenceVisual AcuityAnterior-segment optical coherence tomographyCorneaHOAsPterygium sizeRefractive

Identifiers

PMID42249342
PMCPMC13348517

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.