Evidence map›Paper›PMID 42249287›Full record

ArticleBMC medical imaging2026

Enhanced vertebrae localization in CT volumes: a two-stage deep learning framework.

Hongzhi Liu, Junyang Han, Lingyue Jiang, Yuanxiu Zhang, Xu Wen, Yan Xi, Yudong Zhang, Chunfeng Yang, Rongjun Ge, Hui Tang and 3 more

Abstract read
In one paragraph

Article in BMC medical imaging, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

13 authors.

Hongzhi Liu *School of Computer Science and Engineering, Southeast University, Nanjing, China.
Junyang Han *School of Computer Science and Engineering, Southeast University, Nanjing, China.
Lingyue Jiang *School of Computer Science and Engineering, Southeast University, Nanjing, China.
Yuanxiu ZhangSchool of Computer Science and Engineering, Southeast University, Nanjing, China.
Xu WenSchool of Computer Science and Engineering, Southeast University, Nanjing, China.
Yan XiShanghai First-Imaging Tech, Shanghai, China.
Yudong ZhangSchool of Computer Science and Engineering, Southeast University, Nanjing, China.
Chunfeng YangSchool of Computer Science and Engineering, Southeast University, Nanjing, China.
Rongjun GeSchool of Computer Science and Engineering, Southeast University, Nanjing, China. rongjun_ge@seu.edu.cn.
Hui TangSchool of Computer Science and Engineering, Southeast University, Nanjing, China. corinna@seu.edu.cn.
Shuai WangThe People's Hospital of Yingkou, Yingkou, China. ykdoctor2025@163.com.
Qianjin FengSchool of Biomedical Engineering, Southern Medical University, Guangzhou, China.
Yang ChenSchool of Computer Science and Engineering, Southeast University, Nanjing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundVertebral landmark localization in computed tomography (CT) volumes is crucial for spinal pathological diagnosis, postoperative assessment and surgical planning. However, vertebral localization within high-resolution three-dimensional CT volumes still poses prominent challenges.

methodsThis study introduces a novel two-stage deep learning framework that effectively addresses challenges such as large spatial spans and high morphological similarity of vertebrae. The first stage employs the improved squeeze and excitation V-Net (ISE-VNet) for coarse segmentation of the spinal column. The second stage utilizes a 3D spatial-generalized differential spatial-to-numerical transform (DSNT) module for precise localization of individual vertebrae.

resultsOur framework significantly improves identification rates from 81.15% to 96.32% and reduces localization errors from 7.6 mm to 2.1 mm, outperforming state-of-the-art methods.

conclusionThis approach provides a robust solution for clinical vertebral landmark localization in 3D medical images. This design effectively enables efficient and focused analysis of vertebral local regions and it holds significant value in both scientific research and clinical practice.

Indexed as

Deep LearningImaging, Three-DimensionalSpineTomography, X-Ray ComputedAnatomic LandmarksHumansComputed tomographyDeep learningLandmarks localizationVertebral centroids

Identifiers

PMID42249287
PMCPMC13483603

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.