Observational studyBMC infectious diseases2026
The role of CAR and SII values in determining mortality in COVID-19 patients: a retrospective observational study.
Observational study in BMC infectious diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Early postoperative C-reactive protein-to-albumin ratio for risk stratification of osteomyelitis recurrence after surgical treatment.Frontiers in medicine · 2026Article
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimThis study aimed to determine the relationship between CAR, SII and mortality in patients with coronavirus disease (COVID-19).
methodsThis retrospective study included COVID-19 patients admitted to the emergency department (ED) of a secondary unit care hospital. The relationship between the laboratory parameters (Neutrophil-lymphocyte ratio (NLR) and Platelete-lymphocyte ratio (PLR), fibrinogen, D-dimer, procalcitonin, ferritin, and C-reactive protein, blood urea nitrogen (BUN), creatinine (Crea)), and COVID-19 mortality was examined by comparison with the survival group. Logistic regression analysis was performed to investigate the independent factors affecting mortality.
resultsA total of 1519 COVID-19 patients were analyzed. Mortality was observed in 799 patients (52.6%), and survival was observed in799 patients (52.6%). Neutrophil-lymphocyte ratio (NLR) and Platelete-lymphocyte ratio (PLR) averages were found to be higher and more significant in the mortality group compared to the survival group (p < 0.001). The levels of fibrinogen, D-dimer, procalcitonin, ferritin, and C-reactive protein (CRP), which are acute-phase reactants, were found to be higher and statistically significant in the mortality group than in the survival group (p < 0.001), and blood urea nitrogen (BUN), creatinine (Crea), aspartate aminotransferase (AST), and C-reactive protein (CRP) were found to be independent factors affecting mortality in patients with COVID-19 (p < 0.05).
conclusionsSII and CAR cannot be used as independent predictors of mortality in COVID-19 patients.
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