Evidence map›Paper›PMID 42249222›Full record

ArticleJournal of gastrointestinal cancer2026

Outcomes of Gastric Cancer Surgery in Nonagenarians Compared With Patients Aged 85-89 Years: a Multi-Institutional Study.

Chihiro Onagi, Yoko Oshima, Mari Oba, Sho Sato, Koichi Hayano, Hidejiro Urakami, Sakae Nagaoka, Yasuyuki Seto, Fumiaki Yano, Kimiyasu Yamazaki and 2 more

Abstract readMulticenter StudyComparative Study
PubMed Publisher
In one paragraph

Article in Journal of gastrointestinal cancer, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Chihiro OnagiDepartment of Clinical Oncology, Graduate School of Medicine, Toho University, Tokyo, Japan.ORCID http://orcid.org/0000-0002-3316-4138
Yoko OshimaDepartment of Surgery, School of Medicine, Toho University, 6-11-1 Omori-nishi, Ota-ku, Tokyo, 143-8541, Japan. oshima@med.toho-u.ac.jp.ORCID http://orcid.org/0000-0003-1260-4437
Mari ObaDepartment of Clinical Data Science, Clinical Research & Education Promotion Division, National Center of Neurology and Psychiatry, Tokyo, Japan.
Sho SatoDepartment of Surgery, Yokohama City University Gastroenterological Center, Yokohama, Japan.
Koichi HayanoDepartment of Frontier Surgery, Chiba University Graduate School of Medicine, Chiba, Japan.
Hidejiro UrakamiDepartment of Surgery, National Hospital Organization Tokyo Medical Center, Tokyo, Japan.
Sakae NagaokaDepartment of Gastroesophageal Surgery, Japanese Red Cross Medical Center, Tokyo, Japan.
Yasuyuki SetoDepartment of Stomach and Esophageal Surgery, The University of Tokyo Hospital, Tokyo, Japan.
Fumiaki YanoDepartment of Surgery, The Jikei University School of Medicine, Tokyo, Japan.
Kimiyasu YamazakiDivision of Gastroenterological & General Surgery, Department of Surgery, School of Medicine, Showa University, Tokyo, Japan.
Motomu TanakaDepartment of Surgery, NTT Medical Center Tokyo, Tokyo, Japan.
Hideaki ShimadaDepartment of Clinical Oncology, Graduate School of Medicine, Toho University, Tokyo, Japan.ORCID http://orcid.org/0000-0002-1990-8217

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeSeveral reports have assessed the clinical characteristics of elderly patients aged 85 years or older who had gastric cancer. However, there are only a few reports targeting patients aged ≥ 90 years.

methodsThis multi-institutional study included 596 elderly patients with gastric cancer who were treated surgically between 2000 and 2021. The clinicopathological characteristics and long-term prognosis of two patient groups 85-89-year-old group (85-89 group, n = 496) and ≥ 90-year-old group (90 + group, n = 100) were compared.

resultsThe 90 + group had a significantly lower overall survival and disease-specific survival than the 85-89 group. Based on the multivariate analysis, in the 85-89 group, American Society of Anesthesiologists physical status score of 3 (P < 0.01), stage III/IV disease (P < 0.01), reduced extent of dissection (P = 0.04), and Clavien-Dindo grade III or higher complication (P = 0.02) were independent poor prognostic factors. Further, in the 90 + group, male sex (P < 0.01), low prognostic nutritional index (< 40) (P = 0.02), and total gastrectomy (P < 0.01) were independent poor prognostic factors.

conclusionsThe poor prognostic factors differed between the 85-89 group and 90 + group. In the 90 + group, male sex, low prognostic nutritional index, and total gastrectomy were associated with overall survival. These factors may aid postoperative risk stratification and surgical planning in this age group, but do not by themselves determine surgical candidacy.

Indexed as

GastrectomyPostoperative ComplicationsStomach NeoplasmsAged, 80 and overAge FactorsFemaleHumansMaleNeoplasm StagingPrognosisRetrospective StudiesSurvival RateTreatment OutcomeGastric cancerMulti-institutional studyOver 90 years oldPrognosisPrognostic nutritional index

Identifiers

PMID42249222

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