Evidence map›Paper›PMID 42249094›Full record

ArticleVirchows Archiv : an international journal of pathology2026

Granulomatous prostatitis as a cause of elevated PI-RADS scores on multiparametric MRI: insights from a single institution cohort.

Robert G Colef, Adam T Froemming, Naoki Takahashi, Stephen A Boorjian, Aditya Raghunathan, Burak Tekin, Rafael E Jimenez, John C Cheville, Sounak Gupta

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Article in Virchows Archiv : an international journal of pathology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Robert G ColefDepartment of Laboratory Medicine and Pathology, Mayo Clinic, 200 First Street, Southwest, Rochester, MN, 55905, USA.
Adam T FroemmingDepartment of Radiology, Mayo Clinic, Rochester, MN, USA.
Naoki TakahashiDepartment of Radiology, Mayo Clinic, Rochester, MN, USA.
Stephen A BoorjianDepartment of Urology, Mayo Clinic, Rochester, MN, USA.
Aditya RaghunathanDepartment of Laboratory Medicine and Pathology, Mayo Clinic, 200 First Street, Southwest, Rochester, MN, 55905, USA.
Burak TekinDepartment of Laboratory Medicine and Pathology, Mayo Clinic, 200 First Street, Southwest, Rochester, MN, 55905, USA.
Rafael E JimenezDepartment of Laboratory Medicine and Pathology, Mayo Clinic, 200 First Street, Southwest, Rochester, MN, 55905, USA.
John C ChevilleDepartment of Laboratory Medicine and Pathology, Mayo Clinic, 200 First Street, Southwest, Rochester, MN, 55905, USA.
Sounak GuptaDepartment of Laboratory Medicine and Pathology, Mayo Clinic, 200 First Street, Southwest, Rochester, MN, 55905, USA. gupta.sounak@mayo.edu.ORCID http://orcid.org/0000-0001-5163-6955

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Granulomatous prostatitis (GP) frequently mimics prostatic adenocarcinoma on multiparametric MRI (mpMRI), producing elevated PI-RADS scores and diagnostic challenges. We retrospectively analyzed 63 patients with biopsy-proven GP (without concurrent prostate cancer) and paired mpMRI (2019-2025) to correlate radiologic and histopathologic findings. Median age was 66 years (range 41-80), median PSA 6.2 ng/mL (range 0.1-26.4), and median percentage of biopsy parts involved (PPI) was 36% (range 6-100%). PI-RADS distribution: 2 (14%), 3 (22%), 4 (24%), 5 (40%). High PI-RADS scores (4-5, n = 40, 63%) correlated with higher median PPI (48% vs. 17%, p = 0.01) vs. low PI-RADS scores (2-3, n = 23, 37%), but not PSA (6.4 vs. 5.3 ng/mL, p = 0.68). Among high PI-RADS cases, 25% had prior BCG therapy. One patient with sarcoidosis presented with PI-RADS 5 and 93% PPI. GP produces a broad PI-RADS spectrum; recognizing this imaging variability is essential for accurate diagnosis and avoiding unnecessary procedures.

Indexed as

Bacillus Calmette-GuérinBCGGranulomatous prostatitisMultiparametric MRIPI-RADSSarcoidosis

Identifiers

PMID42249094

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.