Evidence map›Paper›PMID 42248988›Full record

ArticleScientific reports2026

Contrast enhanced CT and MRI interchangeably reflect tumor characteristics in murine pancreatic cancer.

Lea Würfel, Peter Niehaus, Geoffrey J Topping, Mariia Semina, Markus Mittelhäuser, Susanne Kossatz, Marina Lesina, Fabian Lohöfer, Franz Schilling, Uwe Karst and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Lea WürfelInstitute of Diagnostic and Interventional Radiology, TUM School of Medicine and Health, TUM University Hospital Rechts der Isar, Technical University of Munich, Munich, Germany. lea.wuerfel@tum.de.
Peter NiehausInstitute of Inorganic and Analytical Chemistry, University of Muenster, Muenster, Germany.
Geoffrey J ToppingDepartment of Nuclear Medicine, TUM School of Medicine and Health, TUM University Hospital Rechts der Isar, Technical University of Munich, Munich, Germany.
Mariia SeminaInstitute of Diagnostic and Interventional Radiology, TUM School of Medicine and Health, TUM University Hospital Rechts der Isar, Technical University of Munich, Munich, Germany.
Markus MittelhäuserDepartment of Nuclear Medicine, TUM School of Medicine and Health, TUM University Hospital Rechts der Isar, Technical University of Munich, Munich, Germany.
Susanne KossatzDepartment of Nuclear Medicine, TUM School of Medicine and Health, TUM University Hospital Rechts der Isar, Technical University of Munich, Munich, Germany.
Marina LesinaInstitute for Tumor metabolism, Comprehensive Cancer Center Munich TUM, TUM School of Medicine and Health, TUM University Hospital Rechts der Isar, Technical University of Munich, Munich, Germany.
Fabian LohöferInstitute of Diagnostic and Interventional Radiology, TUM School of Medicine and Health, TUM University Hospital Rechts der Isar, Technical University of Munich, Munich, Germany.
Franz SchillingDepartment of Nuclear Medicine, TUM School of Medicine and Health, TUM University Hospital Rechts der Isar, Technical University of Munich, Munich, Germany.
Uwe KarstInstitute of Inorganic and Analytical Chemistry, University of Muenster, Muenster, Germany.
Rickmer BrarenInstitute of Diagnostic and Interventional Radiology, TUM School of Medicine and Health, TUM University Hospital Rechts der Isar, Technical University of Munich, Munich, Germany. rbraren@tum.de.
Irina HeidInstitute of Diagnostic and Interventional Radiology, TUM School of Medicine and Health, TUM University Hospital Rechts der Isar, Technical University of Munich, Munich, Germany. irina.heid@tum.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Contrast-enhanced computed tomography (CE-CT) and dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) are commonly used for tissue characterization, with CE-CT typically preferred in human studies and DCE-MRI in murine models. This raises the question of comparability of intra-and cross-species study results, as techniques differ and signal intensities following contrast agent (CA) administration reflect a complex interplay of systemic physiology and local tissue characteristics. This pilot study compares in vivo mean values of regions of interest (ROIs) obtained from CE-µCT (NanoScan

Indexed as

Carcinoma, Pancreatic DuctalDynamic Contrast Enhanced Magnetic Resonance ImagingPancreatic NeoplasmsTomography, X-Ray ComputedAnimalsContrast MediaDisease Models, AnimalFemaleMiceContrast MediaCE-CTDCE-MRIGadoliniumIodineLA-ICP-MSPDAC

Identifiers

PMID42248988
PMCPMC13241501

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.