Evidence map›Paper›PMID 42248969›Full record

ArticleScientific reports2026

Induced chromosomal instability in triple negative breast cancer cells promotes M2-like polarization of macrophages.

Ruifang Tian, Siqi Zheng, Floris Foijer

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ruifang TianEuropean Research Institute for the Biology of Ageing, University Groningen, University Medical Center Groningen, NL, 9713 AV, Groningen, the Netherlands.
Siqi ZhengEuropean Research Institute for the Biology of Ageing, University Groningen, University Medical Center Groningen, NL, 9713 AV, Groningen, the Netherlands.
Floris FoijerEuropean Research Institute for the Biology of Ageing, University Groningen, University Medical Center Groningen, NL, 9713 AV, Groningen, the Netherlands. f.foijer@umcg.nl.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chromosomal instability (CIN) is a defining feature of triple-negative breast cancer (TNBC) and is increasingly recognized as a driver of tumor evolution and immune escape. However, how CIN

Indexed as

Chromosomal InstabilityMacrophagesTriple Negative Breast NeoplasmsCell Line, TumorCell MovementCoculture TechniquesFemaleHumansMacrophage ActivationMDA-MB-231 CellsMorpholinesPurines2-(4-morpholinoanilino)-6-cyclohexylaminopurineMorpholinesPurinesChromosomal instabilityMigrationTriple-negative breast cancerTumor-associated macrophagesTumor microenvironment

Identifiers

PMID42248969
PMCPMC13482341

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.