ArticleScientific reports2026
The effect of comorbidity and frailty on dietary intake and protein losses in end-stage kidney disease patients undergoing peritoneal dialysis.
Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
End-stage kidney disease (ESKD) patients are advised to follow restricted diets, increasing their risk of malnutrition. We aimed to determine whether co-morbidity and frailty affected dietary intake or protein losses in ESKD patients treated with peritoneal dialysis (PD). We assessed 42 PD patients (mean age 62 ± 16 years) for malnutrition, using the Global Leadership Initiative in Malnutrition (GLIM) criteria, 24-hour dietary recall, bioimpedance, and hand grip strength (HGS), and measured effluent dialysate nitrogen losses. The malnutrition rate was 43%, significantly associated with heart failure (HF) odds ratio (OR) 22.6 (95% Confidence Interval (CI):2.0-259.5, p = 0.012) and low appendicular lean mass index (ALMI) OR 0.13 (95% CI:0.03-0.55, p = 0.006). Sarcopenia was associated with lower dietary protein intake (DPI) (p < 0.05), and decreased protein losses (p < 0.05), whereas Frailty was associated with older age (p < 0.001), greater malnutrition risk (p < 0.05) and reduced HGS (p < 0.05). Diabetic patients also had higher malnutrition risk (p < 0.01). HF was associated with male gender (p < 0.05), and lower body fat (p < 0.05). Increasing numbers of older more co-morbid ESKD patients are being treated with PD, and those with sarcopenia, frailty, diabetes, and HF are at an increased risk of malnutrition. These findings highlight the need for more individualized nutritional assessments.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.