Evidence map›Paper›PMID 42248738›Full record

ArticleTrends in endocrinology and metabolism: TEM2026

Decoding growth hormone actions on human growth plate stem cells.

Shion Orikasa, Noriaki Ono

Abstract read
In one paragraph

Article in Trends in endocrinology and metabolism: TEM, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Shion OrikasaUniversity of Texas Health Science Center at Houston (UTHealth Houston) School of Dentistry, Houston, TX, USA.
Noriaki OnoUniversity of Texas Health Science Center at Houston (UTHealth Houston) School of Dentistry, Houston, TX, USA. Electronic address: noriaki.ono@uth.tmc.edu.

Funding

Skeletal stem cell plasticity in craniofacial bone diseases.R35DE034348 · NIDCR · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI Noriaki Ono · 2024 to 2026
$3.1M
NIDCR NIH HHS R35 DE034348
6 · The paper itself

Abstract

The epiphyseal growth plate is the key target of growth hormone (GH) therapy. Although growth plate stem cells are well defined in mice, their presence in humans was unclear. Using rare surgical specimens, the study by Chu et al. reveals conserved, GH-responsive stem cells in the human pubertal growth plate.

Indexed as

Growth PlateHuman Growth HormoneStem CellsAnimalsHumansHuman Growth Hormone

Identifiers

PMID42248738
PMCPMC13245359

What OpenQuestion holds

Textmetadata
LicenceTDM
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.