Evidence map›Paper›PMID 42248455›Full record

ArticleThe Journal of biological chemistry2026

Oleoylethanolamide enhances regulatory T Cell function to accelerate plaque regression in atherosclerosis via PPARα activation.

Tong Ren, Yanchao Jiao, Le Zhang, Yijun Liu, Xilin Jiang, Lu Peng, Changsheng Yan, Jianbo Jia, Xin Jin

Abstract read
In one paragraph

Article in The Journal of biological chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Tong RenXiamen Cardiovascular Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, China.
Yanchao JiaoDepartment of Otolaryngology, Zhongshan Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, China.
Le ZhangXiamen Cardiovascular Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, China.
Yijun LiuXiamen Cardiovascular Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, China.
Xilin JiangXiamen Cardiovascular Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, China.
Lu PengXiamen Cardiovascular Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, China.
Changsheng YanDepartment of Emergency, Huashan Hospital, Fudan University, Shanghai, China. Electronic address: 724015096@qq.com.
Jianbo JiaDepartment of Breast Surgery, Zhongshan Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, China. Electronic address: 18650181203@163.com.
Xin JinXiamen Cardiovascular Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, China. Electronic address: XinJXiamen@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Regulatory T cells (Tregs) are essential for maintaining immune balance and limiting inflammatory damage within atherosclerotic plaques. Although the endogenous lipid mediator oleoylethanolamide (OEA) has reported anti-inflammatory and metabolic benefits, its effects on Treg differentiation and function during atherosclerosis are incompletely defined. Here, we tested OEA using in vitro naive CD4

Indexed as

AtherosclerosisEndocannabinoidsOleic AcidsPlaque, AtheroscleroticPPAR alphaT-Lymphocytes, RegulatoryAnimalsCell DifferentiationMaleMiceMice, Inbred C57BLEndocannabinoidsOleic AcidsoleoylethanolamidePPAR alphaatherosclerosisOEAPPARαRORγt

Identifiers

PMID42248455
PMCPMC13332470

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.