Evidence map›Paper›PMID 42247637›Full record

ArticleJournal of speech, language, and hearing research : JSLHR2026

Narrative Discourse Predictors of Response to Naming Intervention in Aphasia.

Dirk B den Ouden, Laura Giglio, Sigfus Kristinsson, Leonardo Bonilha, Deena Schwen Blackett, Brielle C Stark, Janina Wilmskoetter, Julius Fridriksson

Abstract read
In one paragraph

Article in Journal of speech, language, and hearing research : JSLHR, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Dirk B den OudenUniversity of South Carolina, Columbia.ORCID 0000-0001-6971-7606
Laura GiglioUniversity of South Carolina, Columbia.
Sigfus KristinssonUniversity of South Carolina, Columbia.ORCID 0000-0002-0459-5369
Leonardo BonilhaUniversity of South Carolina, Columbia.
Deena Schwen BlackettUniversity of Central Florida, Orlando.ORCID 0000-0002-7769-5870
Brielle C StarkIndiana University, Bloomington.ORCID 0000-0002-7001-8324
Janina WilmskoetterMedical University of South Carolina, Charleston.ORCID 0000-0002-1083-7301
Julius FridrikssonUniversity of South Carolina, Columbia.ORCID 0000-0001-9255-2045

Funding

Telerehab for Aphasia (TERRA)P50DC014664 · NIDCD · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI HICKOK, GREGORY · 2016 to 2025
$25.0M
NIDCD NIH HHS P50 DC014664
6 · The paper itself

Abstract

purposeWhile aphasia treatment studies commonly use picture-naming performance as an outcome measure, narrative discourse better reflects functional language use. Discourse variables may also hold prognostic value for naming treatment response, but their predictive role remains underexplored.

methodWe analyzed baseline and posttreatment narrative discourse samples from 95 chronic stroke survivors with aphasia enrolled in a lexical retrieval intervention study. Participants received 3 weeks each of phonological and semantic naming therapy in a crossover design. The Cinderella story retells were analyzed for a range of discourse features: mean length of utterance, words per minute, verbs per utterance, propositional density, type-token ratio, core lexicon, main concepts analysis, and error ratios. We used univariate (generalized) binomial and linear mixed-effects modeling with multiple predictors to assess whether baseline discourse variables predicted naming gains on the Philadelphia Naming Test and whether discourse variables themselves changed following treatment.

resultsHigher aphasia severity and lower baseline propositional density predicted greater naming gains across time points and treatment types. Gains after phonological therapy were also predicted by higher baseline core lexicon production. Posttreatment discourse showed gains in mean length of utterance, words per minute, and core lexicon, which were maintained at 6 months, while phonological errors declined only at follow-up. Phonological treatment led to increases in words per minute.

conclusionsDiscourse variables reflecting propositional efficiency and lexical appropriateness uniquely predict treatment response beyond general aphasia severity. Lexical retrieval therapy generalizes to improvements in narrative discourse, underscoring the clinical value of incorporating discourse-level measures in aphasia assessment and treatment outcome evaluation. SUPPLEMENTAL MATERIAL: https://doi.org/10.23641/asha.32568822.

Indexed as

AphasiaLanguage TherapyNarrationAgedCross-Over StudiesFemaleHumansLanguage TestsMaleMiddle AgedPhoneticsSemanticsStrokeTreatment Outcome

Identifiers

PMID42247637
PMCPMC13371937

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.