Evidence map›Paper›PMID 42247512›Full record

ArticleScience advances2026

A potato late blight pathogen effector interacts with ENTH-domain protein TOL9a and an activated helper NLR to suppress immunity.

Jogi Madhuprakash, AmirAli Toghani, Hsuan Pai, Madia Harvey, Adam R Bentham, Benjamin A Seager, Enoch Lok Him Yuen, Juan Carlos De la Concepción, David M Lawson, Clare E M Stevenson and 6 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Science advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Plant NLRs are getting into higher-order architectures.The Plant journal : for cell and molecular biology · 2026
    Review
  3. Article
  4. Deciphering the Molecular Interplay Between RXLR-EncodedInternational journal of molecular sciences · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Jogi MadhuprakashThe Sainsbury Laboratory, University of East Anglia, Norwich Research Park, Norwich, UK.ORCID 0000-0001-6491-0423
AmirAli ToghaniThe Sainsbury Laboratory, University of East Anglia, Norwich Research Park, Norwich, UK.ORCID 0000-0002-0644-699X
Hsuan PaiThe Sainsbury Laboratory, University of East Anglia, Norwich Research Park, Norwich, UK.ORCID 0000-0002-7284-6131
Madia HarveyThe Sainsbury Laboratory, University of East Anglia, Norwich Research Park, Norwich, UK.ORCID 0000-0002-7105-9857
Adam R BenthamDepartment of Biochemistry and Metabolism, John Innes Centre, Norwich Research Park, Norwich, UK.ORCID 0000-0001-5906-0962
Benjamin A SeagerThe Sainsbury Laboratory, University of East Anglia, Norwich Research Park, Norwich, UK.ORCID 0009-0000-3161-1849
Enoch Lok Him YuenDepartment of Life Sciences, Imperial College, London, UK.ORCID 0000-0002-7933-0605
Juan Carlos De la ConcepciónThe Sainsbury Laboratory, University of East Anglia, Norwich Research Park, Norwich, UK.ORCID 0000-0002-7642-8375
David M LawsonDepartment of Biochemistry and Metabolism, John Innes Centre, Norwich Research Park, Norwich, UK.ORCID 0000-0002-7637-4303
Clare E M StevensonDepartment of Biochemistry and Metabolism, John Innes Centre, Norwich Research Park, Norwich, UK.ORCID 0000-0001-6695-8201
Angel Vergara-CrucesThe Sainsbury Laboratory, University of East Anglia, Norwich Research Park, Norwich, UK.ORCID 0000-0003-0222-203X
Lida DerevninaThe Sainsbury Laboratory, University of East Anglia, Norwich Research Park, Norwich, UK.ORCID 0000-0001-7983-4187
Tolga O BozkurtDepartment of Life Sciences, Imperial College, London, UK.ORCID 0000-0003-0507-6875
Mark J BanfieldDepartment of Biochemistry and Metabolism, John Innes Centre, Norwich Research Park, Norwich, UK.ORCID 0000-0001-8921-3835
Sophien KamounThe Sainsbury Laboratory, University of East Anglia, Norwich Research Park, Norwich, UK.ORCID 0000-0002-0290-0315
Mauricio P ContrerasThe Sainsbury Laboratory, University of East Anglia, Norwich Research Park, Norwich, UK.ORCID 0000-0001-6002-0730

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pathogens counteract central nodes of NLR immune receptor networks to suppress immunity. However, the mechanisms by which pathogens hijack helper NLR pathways are poorly understood. We show that an effector from the late blight pathogen

Indexed as

Host-Pathogen InteractionsInnate Immunity RecognitionNLR ProteinsPhytophthora infestansPlant DiseasesSolanum tuberosumModels, MolecularProtein BindingProtein DomainsNLR Proteins

Identifiers

PMID42247512
PMCPMC13240173

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.