Evidence map›Paper›PMID 42247436›Full record

ArticlePloS one2026

Clinicopathological features and ethnic disparities of melanoma in the United Arab Emirates: 2017-2025.

Jonathan Mokhtar, Nada Alsuwaidi, Nada Hassane, Rose Mary Eapen, Hind Aljanaahi, Dalia AlDhamin, Tannaz Rahbari, Ghazal Talal Saeed, Zainab Abdulla Al Darwish, Sara Almalik and 3 more

Abstract read
In one paragraph

Article in PloS one, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Jonathan MokhtarMohammed Bin Rashid University of Medicine and Health Sciences, College of Medicine (MBRU-CoM), Dubai, United Arab Emirates.ORCID https://orcid.org/0009-0005-8786-5246
Nada AlsuwaidiMohammed Bin Rashid University of Medicine and Health Sciences, College of Medicine (MBRU-CoM), Dubai, United Arab Emirates.
Nada HassaneMohammed Bin Rashid University of Medicine and Health Sciences, College of Medicine (MBRU-CoM), Dubai, United Arab Emirates.
Rose Mary EapenInternational Dermpath Consult FZ-LLC, Dubai, United Arab Emirates.ORCID https://orcid.org/0009-0008-0837-9349
Hind AljanaahiMohammed Bin Rashid University of Medicine and Health Sciences, College of Medicine (MBRU-CoM), Dubai, United Arab Emirates.
Dalia AlDhaminMohammed Bin Rashid University of Medicine and Health Sciences, College of Medicine (MBRU-CoM), Dubai, United Arab Emirates.
Tannaz RahbariMohammed Bin Rashid University of Medicine and Health Sciences, College of Medicine (MBRU-CoM), Dubai, United Arab Emirates.
Ghazal Talal SaeedMohammed Bin Rashid University of Medicine and Health Sciences, College of Medicine (MBRU-CoM), Dubai, United Arab Emirates.
Zainab Abdulla Al DarwishDepartment of Dermatology and Aesthetic Center, Rashid Hospital, Dubai Health, Dubai, United Arab Emirates.
Sara AlmalikMohammed Bin Rashid University of Medicine and Health Sciences, College of Medicine (MBRU-CoM), Dubai, United Arab Emirates.
Jeyaseelan LakshmananMohammed Bin Rashid University of Medicine and Health Sciences, College of Medicine (MBRU-CoM), Dubai, United Arab Emirates.
Tom LoneyMohammed Bin Rashid University of Medicine and Health Sciences, College of Medicine (MBRU-CoM), Dubai, United Arab Emirates.ORCID https://orcid.org/0000-0003-1687-6587
Reem El-BahtimiInternational Dermpath Consult FZ-LLC, Dubai, United Arab Emirates.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCutaneous melanoma incidence is rising globally, yet clinicopathological data from the high ultraviolet (UV) environment in the United Arab Emirates (UAE), with its diverse expatriate population, remain scarce. This study aims to characterize the histopathological features of cutaneous melanoma in a large, multi-ethnic cohort in the UAE.

methodsThis retrospective cross-sectional study analyzed histopathologically confirmed cases of cutaneous melanoma diagnosed at a specialized dermatopathology laboratory in the UAE from 01/01/2017-01/01/2025. Patient demographics, tumor location, histologic subtype, Clark level, Breslow thickness, mitosis, lymphovascular, and perineural invasion were extracted and analyzed. Descriptive statistics, group comparisons, and multivariable logistic regression were performed using IBM SPSS version 29.0 to identify predictors of thick melanoma (Breslow thickness >1.0 mm).

resultsA total of 597 patients met the inclusion criteria (50.8% male; mean age 47.4 ± 12.3 years). Individuals of European ancestry constituted 73.4% of cases. Superficial spreading melanoma was the predominant subtype (58.5%), and 46.9% of melanomas were thin (≤1.0 mm). Males presented with significantly thicker tumors than females (Breslow thickness of 0.72 ± 1.32 vs. 0.50 ± 0.58 mm; p < 0.01) and exhibited distinct anatomical distributions predominant to the trunk as compared to females with leg predominance. Multivariable analysis confirmed nodular melanoma (OR 18.40; 95% CI [7.08, 47.86]; p < 0.001) as the single strongest independent predictor of thick melanoma.

conclusionMelanoma in the UAE disproportionately affects fair-skinned expatriates and frequently presents with sex-specific clinical patterns. These findings highlight the need for targeted public awareness initiatives to reduce melanoma morbidity and mortality in the region.

Indexed as

MelanomaSkin NeoplasmsAdultAgedCross-Sectional StudiesEthnicityFemaleHumansMaleMiddle AgedRetrospective StudiesUnited Arab EmiratesWhite People

Identifiers

PMID42247436
PMCPMC13240860

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.