Evidence map›Paper›PMID 42247256›Full record

ArticleAnnals of medicine2026

Analysis of risk factors for postoperative wound healing in children with bone cysts.

Muhan Yu, Yuxi Su

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Article in Annals of medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

2 authors.

Muhan YuDepartment of Clinical Laboratory, Children's Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, China International Science and Technology Cooperation Base of Child Development and Critical Disorders, Chongqing Key Laboratory of Pediatric Metabolism and Inflammatory Diseases, Chongqing, China.ORCID 0009-0003-4682-3635
Yuxi SuDepartment of Clinical Laboratory, Children's Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, China International Science and Technology Cooperation Base of Child Development and Critical Disorders, Chongqing Key Laboratory of Pediatric Metabolism and Inflammatory Diseases, Chongqing, China.ORCID 0000-0003-1904-5594

Funding

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6 · The paper itself

Abstract

backgroundBone cysts are common benign bone tumour-like lesions in children and adolescents. Postoperative wound healing complications significantly affect patient outcomes. Current research primarily focuses on cyst recurrence and bone healing, while studies targeting risk factors for poor postoperative wound healing in children are relatively scarce.

methodsThis single-center retrospective cohort analysis included 99 children with bone cysts who were hospitalized and underwent surgical treatment between January 2021 and September 2025. We analyzed these data in November 2025. Univariate analysis and multivariate logistic regression were used to assess the association of demographic, lesion characteristics and surgery-related variables with poor wound healing.

resultsAmong the 99 children, 13 (13.1%) experienced poor wound healing. Multivariate analysis revealed that no or single-dose preoperative antibiotic prophylaxis (OR = 9.808,

conclusionInadequate perioperative antibiotic prophylaxis (either no administration or a single preoperative dose only), physeal involvement of the lesion and prolonged operative time are independent risk factors for poor postoperative wound healing in children. Standardizing antibiotic protocols and identifying high-risk patients based on lesion anatomical characteristics are crucial for reducing the risk of complications.

Indexed as

Antibiotic ProphylaxisBone CystsPostoperative ComplicationsWound HealingAdolescentAnti-Bacterial AgentsChildChild, PreschoolFemaleHumansMaleOperative TimeRetrospective StudiesRisk FactorsSurgical Wound InfectionAnti-Bacterial Agentsanti-bacterial agentsBone cystchildgrowth platerisk factorssurgical wound healing

Identifiers

PMID42247256
PMCPMC13244503

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