Evidence map›Paper›PMID 42247068›Full record

ArticleAIDS and behavior2026

Food Insecurity and Cognitive Performance Among Young People Living With and Without HIV: A Study Across Four African Countries.

Seth Frndak, Nicole Dear, Natalie Burns, Hannah Kibuuka, John Owuoth, Valentine Sing'oei, Jonah Maswai, Emmanuel Bahemana, Zahra Parker, Neha Shah and 5 more

Abstract read
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In one paragraph

Article in AIDS and behavior, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Seth FrndakU.S. Military HIV Research Program, Center for Infectious Disease Research, Walter Reed Army Institute of Research, Silver Spring, MD, USA.ORCID http://orcid.org/0000-0002-2049-2204
Nicole DearU.S. Military HIV Research Program, Center for Infectious Disease Research, Walter Reed Army Institute of Research, Silver Spring, MD, USA.ORCID http://orcid.org/0000-0002-8026-9901
Natalie BurnsU.S. Military HIV Research Program, Center for Infectious Disease Research, Walter Reed Army Institute of Research, Silver Spring, MD, USA. nburns@global-id.org.ORCID http://orcid.org/0000-0002-6952-9581
Hannah KibuukaMakerere University Walter Reed Project, Kampala, Uganda.
John OwuothU.S. Military HIV Research Program, Walter Reed Army Institute of Research Africa, Kisumu, Kenya.
Valentine Sing'oeiU.S. Military HIV Research Program, Walter Reed Army Institute of Research Africa, Kisumu, Kenya.ORCID http://orcid.org/0000-0001-9434-9630
Jonah MaswaiU.S. Military HIV Research Program, Walter Reed Army Institute of Research Africa, Kericho, Kenya.
Emmanuel BahemanaU.S. Military HIV Research Program, Walter Reed Army Institute of Research Africa, Mbeya, Tanzania.
Zahra ParkerHenry M. Jackson Foundation for the Advancement of Military Medicine, Inc., Bethesda, MD, USA.
Neha ShahU.S. Military HIV Research Program, Center for Infectious Disease Research, Walter Reed Army Institute of Research, Silver Spring, MD, USA.ORCID http://orcid.org/0000-0002-9575-9161
Trevor A CrowellU.S. Military HIV Research Program, Center for Infectious Disease Research, Walter Reed Army Institute of Research, Silver Spring, MD, USA.ORCID http://orcid.org/0000-0001-5947-265X
Victor ValcourDepartment of Medicine, Division of Geriatric Medicine, University of California San Francisco, San Francisco, CA, USA.
Julie A AkeU.S. Military HIV Research Program, Center for Infectious Disease Research, Walter Reed Army Institute of Research, Silver Spring, MD, USA.
Elena TsoyDepartment of Neurology, Memory and Aging Center, University of California San Francisco, San Francisco, CA, USA.ORCID http://orcid.org/0000-0001-8786-1791
AFRICOS Study Group

Funding

Understanding Pandemic Evolution through Networked Data (UPEND)RF1MH133442 · NIMH · HENRY M. JACKSON FDN FOR THE ADV MIL/MED · PI CROWELL, TREVOR ADAM · 2023 to 2023
$3.8M
NIMH NIH HHS RF1 MH133442U.S. Department of Defense HT9425-24-2-0020U.S. Department of Defense HT9425-24-3-0004U.S. Department of Defense W81XWH-11-2-0174U.S. Department of Defense W81XWH-18-2-0040
6 · The paper itself

Abstract

Cognitive development in young adulthood among people living with HIV (PLWH) is not well understood, especially in the context of food insecurity (FI). Nutrient-based interventions may have unique cognitive benefits dependent on age and HIV status. Our analysis included participants enrolled in the African Cohort Study (AFRICOS). AFRICOS enrolls PLWH and without HIV (PLWoH) across 12 PEPFAR-supported facilities in Kenya, Nigeria, Tanzania, and Uganda. All participants were 15-27 years old and on antiretroviral therapy (ART) ≥ 6 months if PLWH. Annual neuropsychological assessments included the WHO Auditory Verbal Learning Test (AVLT; learning and memory), Trail Making Test Part A (TMT-A; processing speed), Color Trails 1 (CT1; processing speed), Color Trails 2 (CT2; executive functions), and Verbal Fluency (VF; language generativity). FI was determined by self-reporting not enough to eat or having < 3 meals per day. Linear mixed models assessed independent and interactive effects of age, HIV status, and time-varying FI on longitudinal cognitive outcomes. From 2013 to 2023 we collected data from 1,012 participants, of whom 575 (56.8%) were female and 476 (47.0%) ever FI. Overall, increasing age was associated with better cognitive performance. Despite ART experience, PLWH performed worse than PLWoH on language generativity (VF; β=-0.47, p = 0.032) and executive functions (CT2; β = 8.10, p = 0.004). FI was associated with worse memory performance at younger ages (β

Indexed as

Africa South of the SaharaCognitionDevelopmentFood insecurityHIVYoung people

Identifiers

PMID42247068

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.