Evidence map›Paper›PMID 42246973›Full record

ArticleACS chemical biology2026

Single-Molecule Visualization of DNase I-Mediated DNA Cleavage by High-Speed Atomic Force Microscopy.

Nada Elessawy, Selma Sinan, Hongshan Zhang, Zhenglin Yang, Yi Lu, Ilya J Finkelstein, Yi-Chih Lin

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS chemical biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Nada ElessawyDepartment of Chemistry, University of Texas at Austin, Austin, Texas78712, United States.
Selma SinanDepartment of Molecular Biosciences and Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, Texas78712, United States.
Hongshan ZhangDepartment of Molecular Biosciences and Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, Texas78712, United States.
Zhenglin YangDepartment of Chemistry, University of Texas at Austin, Austin, Texas78712, United States.
Yi LuDepartment of Chemistry, University of Texas at Austin, Austin, Texas78712, United States.ORCID 0000-0003-1221-6709
Ilya J FinkelsteinDepartment of Molecular Biosciences and Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, Texas78712, United States.ORCID 0000-0002-9371-2431
Yi-Chih LinDepartment of Chemistry, University of Texas at Austin, Austin, Texas78712, United States.ORCID 0000-0002-6498-215X

Funding

Design and Selection of Novel Metalloenzymes for Biocatalysis, Bioimaging, and Genetic EngineeringR35GM141931 · NIGMS · UNIVERSITY OF TEXAS AT AUSTIN · PI Yi Lu · 2021 to 2026
$3.5M
Real-time structural and functional studies of SARS-CoV-2 spike proteinsR35GM150528 · NIGMS · UNIVERSITY OF TEXAS AT AUSTIN · PI Yi-Chih Lin · 2023 to 2026
$1.6M
NIGMS NIH HHS R35 GM141931NIGMS NIH HHS R35 GM150528
6 · The paper itself

Abstract

DNase I is a nonspecific endonuclease that preferentially cleaves double-stranded DNA (dsDNA) over single-stranded DNA (ssDNA) in the presence of Ca

Indexed as

Deoxyribonuclease IDNADNA CleavageMicroscopy, Atomic ForceSingle Molecule ImagingDNA, Single-StrandedDeoxyribonuclease IDNADNA, Single-Stranded

Identifiers

PMID42246973
PMCPMC13307592

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.