Evidence map›Paper›PMID 42246911›Full record

ArticleMayo Clinic proceedings2026

Nondialytic Care vs Dialysis Transition on Hospitalization: Outcomes in Veterans With Advanced Chronic Kidney Disease.

Connie M Rhee, Yoko Narasaki, Susan T Crowley, Csaba P Kovesdy, Dana B Mukamel, Amy S You, Matthew Nguyen, Man Kit Michael Siu, Lisa Le, Alejandra Novoa and 2 more

Abstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Mayo Clinic proceedings, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Connie M RheeDivision of Nephrology, David Geffen School of Medicine at UCLA, Los Angeles, CA; Nephrology Section, Veterans Affairs Greater Los Angeles Healthcare System, Los Angeles, CA; Division of Nephrology, Hypertension and Kidney Transplantation Department of Medicine, University of California Irvine School of Medicine, Orange, CA. Electronic address: crhee@mednet.ucla.edu.
Yoko NarasakiDivision of Nephrology, David Geffen School of Medicine at UCLA, Los Angeles, CA; Nephrology Section, Veterans Affairs Greater Los Angeles Healthcare System, Los Angeles, CA.
Susan T CrowleyNephrology Division, Yale University, New Haven, CT; Nephrology Section, West Haven Veterans Affairs Medical Center, New Haven, CT.
Csaba P KovesdyDivision of Nephrology, Department of Medicine, University of Tennessee Health Science Center and Nephrology Section, Memphis Veterans Affairs Medical Center, Memphis, TN.
Dana B MukamelDivision of General Internal Medicine and Primary Care, Department of Medicine, University of California Irvine School of Medicine, Orange, CA.
Amy S YouDivision of Nephrology, David Geffen School of Medicine at UCLA, Los Angeles, CA; Nephrology Section, Veterans Affairs Greater Los Angeles Healthcare System, Los Angeles, CA.
Matthew NguyenNephrology Section, Veterans Affairs Greater Los Angeles Healthcare System, Los Angeles, CA; Division of Nephrology, Hypertension and Kidney Transplantation Department of Medicine, University of California Irvine School of Medicine, Orange, CA.
Man Kit Michael SiuDivision of Nephrology, David Geffen School of Medicine at UCLA, Los Angeles, CA; Nephrology Section, Veterans Affairs Greater Los Angeles Healthcare System, Los Angeles, CA.
Lisa LeDivision of Nephrology, David Geffen School of Medicine at UCLA, Los Angeles, CA; Nephrology Section, Veterans Affairs Greater Los Angeles Healthcare System, Los Angeles, CA.
Alejandra NovoaDivision of Nephrology, David Geffen School of Medicine at UCLA, Los Angeles, CA; Nephrology Section, Veterans Affairs Greater Los Angeles Healthcare System, Los Angeles, CA.
Danh V NguyenNephrology Section, Veterans Affairs Greater Los Angeles Healthcare System, Los Angeles, CA; Division of Nephrology, Hypertension and Kidney Transplantation Department of Medicine, University of California Irvine School of Medicine, Orange, CA.
Kamyar Kalantar-ZadehDivision of Nephrology, Hypertension and Kidney Transplantation Department of Medicine, University of California Irvine School of Medicine, Orange, CA; Division of Nephrology, Lundquist Institute at Harbor-UCLA Medical Center, Torrance, CA; Tibor Rubin Veterans Affairs Long Beach Medical Center, Long Beach, CA; Department of Epidemiology, UCLA Fielding School of Public Health, Los Angeles, CA.

Funding

Multilevel Time-Dynamic Modeling of Hospitalization and Survival in Patients on DialysisR01DK092232 · NIDDK · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI KURUM, ESRA, NGUYEN, DANH V · 2011 to 2025
$4.9M
A Randomized Controlled Trial of Thyroid Hormone Supplementation in Hemodialysis PatientsR01DK122767 · NIDDK · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI RHEE, CONNIE MEEYOUNG · 2019 to 2023
$3.3M
Defining Optimal Transitions of Care in Advanced Kidney Disease: Conservative Management vs. Dialysis ApproachesR01DK124138 · NIDDK · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI KALANTAR-ZADEH, KAMYAR, RHEE, CONNIE MEEYOUNG · 2020 to 2024
$2.9M
Plant-Focused Nutrition in Patients with Diabetes and Chronic Kidney Disease (PLAFOND Study): A Pilot/Feasibility StudyR01DK132875 · NIDDK · LUNDQUIST INSTITUTE FOR BIOMEDICAL INNOVATION AT HARBOR-UCLA MEDICAL CENTER · PI KALANTAR-ZADEH, KAMYAR, RHEE, CONNIE MEEYOUNG · 2023 to 2025
$836k
Continuous Glucose Monitoring in Dialysis Patients to Overcome Dysglycemia Trial (CONDOR TRIAL)R01DK132869 · NIDDK · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI KALANTAR-ZADEH, KAMYAR, RHEE, CONNIE MEEYOUNG · 2023 to 2025
$781k
NIDDK NIH HHS R01 DK092232NIDDK NIH HHS R01 DK122767NIDDK NIH HHS R01 DK124138NIDDK NIH HHS R01 DK132869NIDDK NIH HHS R01 DK132875
6 · The paper itself

Abstract

objectiveTo compare the effects of nondialytic care vs dialysis on hospitalization outcomes in advanced chronic kidney disease (CKD), given that dialysis, as the predominant treatment paradigm for patients with advanced CKD transitioning to end-stage kidney disease, may be associated with high early mortality, health care utilization, and withdrawal. PATIENTS AND

methodsWe examined a national cohort of veterans with advanced CKD (≥2 estimated glomerular filtration rates <25 mL/min per 1.73 m

resultsIn the 1:1 propensity score-matched cohort of 13,020 nondialytic and 13,020 dialysis patients, dialysis transition was associated with higher rates of hospitalization and days hospitalized (reference: nondialytic care): incident rate ratios (95% CIs), 1.64 (1.61 to 1.66) and 1.71 (1.70 to 1.72), respectively. Dialysis was also associated with longer average LOS vs nondialytic care: 8.6 vs 8.1 days, respectively. In secondary analyses of timing of dialysis transition, incrementally earlier dialysis transitions were associated with increasingly higher hospitalization rates vs nondialytic care, with similar patterns observed for rates of days hospitalized and LOS.

conclusionCompared with nondialytic care, dialysis was associated with higher rates of hospitalization and days hospitalized and longer LOS.

Indexed as

HospitalizationKidney Failure, ChronicRenal DialysisRenal Insufficiency, ChronicAgedFemaleGlomerular Filtration RateHumansLength of StayMaleMiddle AgedPropensity ScoreUnited StatesVeterans

Identifiers

PMID42246911
PMCPMC13616424

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.