ArticleSouth African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde2026
Engagement in antenatal and HIV care among pregnant women before and after Option B+ policy implementation in South Africa.
Article in South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- Uptake and retention in HIV care among pregnant and postpartum women living with HIV under different eras of vertical transmission prevention policies in sub-Saharan Africa: a systematic review and meta-analysis.medRxiv : the preprint server for health sciences · 2026Article
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Abstract
backgroundSubstantial gains have been made in South Africa (SA) in the prevention of vertical transmission of HIV over the past decade.
objectiveTo determine whether engagement in antenatal and HIV care among pregnant women living with HIV (WLWH) differed after Option B+ implementation.
methodsWe analysed cohort data from a pregnancy and birth defects surveillance system in KwaZulu-Natal (KZN). We report on two co-primary outcomes related to engagement in HIV care: (i) timing and number of antenatal care (ANC) visits during the pregnancy period; and (ii) timing of antiretroviral therapy (ART) initiation (both self-reported ART use in interviews and observed initiation of treatment in maternal records). The association of policy era on the timing of ANC presentation was assessed using log-binomial regression modelling. We also report proportions initiating ART before or during pregnancy stratified by policy era.
resultsData from 40 357 women, including 16 016 (40%) WLWH were analysed. During the Option B+ era, 24% of pregnant WLWH attended their first antenatal care visit during the first trimester, compared with 16% during the Option B era (relative risk 1.52; 95% confidence interval 1.41 - 1.64). The proportion of WLWH who initiated ART prior to pregnancy was also higher during the Option B+ era than the Option B era, though this result was limited by missing data.
conclusionEngagement in antenatal and HIV care improved after Option B+ implementation. In the Option B+ era, SA has made significant progress toward the goal of eliminating mother-to-child transmission of HIV.
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