Evidence map›Paper›PMID 42246360›Full record

ArticleDermatology online journal2026

Aquagenic wrinkling of the palms in a healthy adolescent.

César Bimbi, Amanda Nichele, João Pedro Locatelli Cezar, Camila Machado, André Anjos da Silva

Abstract readCase Reports
PubMed Publisher
In one paragraph

Article in Dermatology online journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

César BimbiPrivate Clinic, Dermatologia Médica & Laser Clinic, Porto Alegre, Rio Grande do Sul, Brazil.
Amanda NicheleSchool of Medicine, Universidade do Vale do Rio dos Sinos (UNISINOS), São Leopoldo, Brazil.
João Pedro Locatelli CezarDepartment of Pediatrics, Universidade do Vale dos Sinos (UNISINOS), São Leopoldo, Brazil.
Camila MachadoDepartment of Pediatrics, Universidade do Vale dos Sinos (UNISINOS), São Leopoldo, Brazil.
André Anjos da SilvaSchool of Medicine, Universidade do Vale do Rio dos Sinos (UNISINOS), São Leopoldo, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aquagenic wrinkling of the palms (AWP) is a rare dermatologic condition characterized by rapid wrinkling, edema, and papules on the palms after brief water exposure. It is commonly associated with cystic fibrosis (CF) or CF carrier status but can also occur in individuals without these conditions. We report a healthy 12-year-old girl who presented with AWP without a family history of CF or related symptoms. After 4 minutes of water immersion, she exhibited typical wrinkling and translucent papules on the palms, which resolved completely within 15 minutes. A sweat test for CF was negative. The patient was managed with moisturizers and advised to minimize prolonged water exposure. This case highlights AWP as a potential early marker for CF or carrier status, even in the absence of other symptoms. Recognition of AWP may guide genetic screening and early intervention, underscoring the role of dermatologists in identifying this condition and facilitating timely diagnosis and management of CF.

Indexed as

Hand DermatosesImmersionSkin AgingWaterChildCystic FibrosisFemaleHandHumansWaterpediatricsrare diseasesskin diseases

Identifiers

PMID42246360

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.