Evidence map›Paper›PMID 42246324›Full record

ArticleDermatology online journal2026

Adverse dermatologic effects of erdafitinib in a patient with metastatic urothelial carcinoma.

Megan Johnson, Marie Clark, Carli Whittington, Edita Newton

Abstract readCase Reports
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In one paragraph

Article in Dermatology online journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Megan JohnsonIndiana University School of Medicine, Indianapolis, IN, USA.
Marie ClarkDepartment of Dermatology, Indiana University School of Medicine, Indianapolis, IN, USA.
Carli WhittingtonDepartment of Dermatology, Indiana University School of Medicine, Indianapolis, IN, USA.
Edita NewtonDepartment of Dermatology, Indiana University School of Medicine, Indianapolis, IN, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Erdafitinib is a fibroblast growth factor receptor 1-4 inhibitor used for locally advanced or metastatic urothelial carcinoma in patients who have experienced disease progression after at least 1 prior systemic therapy. Various cutaneous side effects of erdafitinib have been reported, most commonly stomatitis and nail changes such as onycholysis, nail dystrophy, and paronychia. However, onychomadesis is a rarer nail toxicity that can cause significant discomfort and may necessitate treatment interruption. We present the case of a 61-year-old White man with metastatic urothelial carcinoma treated with 8 mg of erdafitinib daily who developed diffuse onychomadesis within a few months of initiating therapy. Awareness of the potential cutaneous side effects of erdafitinib and timely referral for specialty dermatologic care are important to allow treatment continuation.

Indexed as

Antineoplastic AgentsCarcinoma, Transitional CellNail DiseasesProtein Kinase InhibitorsPyrazolesQuinoxalinesUrinary Bladder NeoplasmsHumansMaleMiddle AgedAntineoplastic AgentserdafitinibProtein Kinase InhibitorsPyrazolesQuinoxalineserdafitinibnailsoncologyonychomadesistherapeutics

Identifiers

PMID42246324

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.