Evidence map›Paper›PMID 42246204›Full record

ArticleBritish journal of haematology2026

BCL-2 and MCL1 co-inhibition enhances glucocorticoid therapy in preclinical models of infant KMT2A-rearranged acute lymphoblastic leukaemia.

Mawar Karsa, Ayu Karsa, Dayna Spurling, Lin Xiao, Emma Ronca, Angelika Bongers, Weiman Gao, Andrew J Gifford, Ali El-Ayoubi, Laurence C Cheung and 10 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in British journal of haematology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Mawar KarsaChildren's Cancer Institute at Minderoo Children's Comprehensive Cancer Centre, UNSW Sydney, Sydney, New South Wales, Australia.
Ayu KarsaChildren's Cancer Institute at Minderoo Children's Comprehensive Cancer Centre, UNSW Sydney, Sydney, New South Wales, Australia.
Dayna SpurlingChildren's Cancer Institute at Minderoo Children's Comprehensive Cancer Centre, UNSW Sydney, Sydney, New South Wales, Australia.
Lin XiaoChildren's Cancer Institute at Minderoo Children's Comprehensive Cancer Centre, UNSW Sydney, Sydney, New South Wales, Australia.
Emma RoncaChildren's Cancer Institute at Minderoo Children's Comprehensive Cancer Centre, UNSW Sydney, Sydney, New South Wales, Australia.
Angelika BongersChildren's Cancer Institute at Minderoo Children's Comprehensive Cancer Centre, UNSW Sydney, Sydney, New South Wales, Australia.
Weiman GaoChildren's Cancer Institute at Minderoo Children's Comprehensive Cancer Centre, UNSW Sydney, Sydney, New South Wales, Australia.
Andrew J GiffordChildren's Cancer Institute at Minderoo Children's Comprehensive Cancer Centre, UNSW Sydney, Sydney, New South Wales, Australia.
Ali El-AyoubiChildren's Cancer Institute at Minderoo Children's Comprehensive Cancer Centre, UNSW Sydney, Sydney, New South Wales, Australia.
Laurence C CheungLeukaemia Translational Research Laboratory, WA Kids Cancer Centre, The Kids Research Institute Australia, Perth, Western Australia, Australia.
Rishi S KotechaLeukaemia Translational Research Laboratory, WA Kids Cancer Centre, The Kids Research Institute Australia, Perth, Western Australia, Australia.ORCID https://orcid.org/0000-0003-1836-4075
Richard B LockChildren's Cancer Institute at Minderoo Children's Comprehensive Cancer Centre, UNSW Sydney, Sydney, New South Wales, Australia.
Charis E TehWalter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, Australia.
Guillaume LesseneWalter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, Australia.
Murray D NorrisChildren's Cancer Institute at Minderoo Children's Comprehensive Cancer Centre, UNSW Sydney, Sydney, New South Wales, Australia.
Andrew WeiWalter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, Australia.
Michelle HaberChildren's Cancer Institute at Minderoo Children's Comprehensive Cancer Centre, UNSW Sydney, Sydney, New South Wales, Australia.
Michelle J HendersonChildren's Cancer Institute at Minderoo Children's Comprehensive Cancer Centre, UNSW Sydney, Sydney, New South Wales, Australia.
Donia M MoujalledWalter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, Australia.ORCID https://orcid.org/0000-0002-1076-3496
Klaartje SomersChildren's Cancer Institute at Minderoo Children's Comprehensive Cancer Centre, UNSW Sydney, Sydney, New South Wales, Australia.

Funding

Kids Cancer Alliance
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

BCL‐2KMT2A‐rearrangedleukaemiaMCL1venetoclax

Identifiers

PMID42246204
PMCPMC13461956

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.