Evidence map›Paper›PMID 42246046›Full record

ArticleFrontiers in neurology

Successful management of cavernous sinus thrombosis without anticoagulation: a neuro-ophthalmologic case report.

Xiao-Ou Wang, Cui-Zhu Hu, Yi-Meng Niu, Wen Tian

Abstract readCase Reports
In one paragraph

Article in Frontiers in neurology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Xiao-Ou WangDepartment of Geriatric, The First Hospital of China Medical University, Shenyang, China.
Cui-Zhu HuDepartment of Geriatric, The First Hospital of China Medical University, Shenyang, China.
Yi-Meng NiuDepartment of Geriatric, The First Hospital of China Medical University, Shenyang, China.
Wen TianDepartment of Geriatric, The First Hospital of China Medical University, Shenyang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cavernous sinus thrombosis (CST) is a rare and life-threatening neuro-ophthalmologic emergency. The role of adjunctive anticoagulation in infection-driven CST-especially when patients respond rapidly to antibiotics-remains a clinically significant dilemma. We report the case of a 50-year-old male presenting with acute right periorbital swelling, proptosis, ocular pain, and headache. Magnetic resonance imaging (MRI) confirmed right cavernous sinus thrombosis secondary to bilateral sinusitis. After multidisciplinary review, anticoagulation was withheld due to the patient's prompt clinical improvement on targeted intravenous antibiotics (meropenem/ertapenem) and concerns regarding bleeding risk. Complete symptomatic and radiological recovery was achieved, as evidenced by serial MRI follow-up over eight months. This case demonstrates that in selected patients with septic CST and a treatable infectious source, aggressive antibiotic therapy alone may lead to full resolution. It highlights the value of individualized management and contributes to the ongoing discussion on the timing and necessity of anticoagulation in this complex condition.

Indexed as

antibiotic therapyanticoagulationcase reportcavernous sinus thrombosismagnetic resonance imagingneuro-ophthalmologyseptic thrombosis

Identifiers

PMID42246046
PMCPMC13229824

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.