ArticleFrontiers in neurology
Factor analysis validates the internal structure of the Cerebellar Neuropsychiatric Rating Scale Version 2 and the five domains of cerebellar neuropsychiatry.
Article in Frontiers in neurology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: The Cerebellar Neuropsychiatric Rating Scale Version 2 (CNRS-2) measures affective symptoms in cerebellar disease patients across five postulated domains of attentional control, emotional control, autism spectrum, psychosis spectrum, and social skill set, each with overshoot and undershoot symptom subdomains. A data-driven approach is needed to test our Objectives: To explore the latent structure of the CNRS-2 and evaluate the five-domain and overshoot-undershoot structure of the scale items. Methods: CNRS-2 was administered to 279 cerebellar subjects. Data suitability for factor analysis was assessed. Eigenvalues and parallel analysis scree plots were evaluated for factor extraction. Exploratory factor analysis (EFA) was performed to identify an optimal factor solution. The EFA-derived solution and our Results: We extracted 5, 6, and 7 factors based on eigenvalues and parallel analysis. EFA indicated that a six-factor solution best balanced statistical fit and theoretical interpretability. CFA on this EFA-derived solution and on our Conclusion: Factor analysis of the items comprising CNRS-2 provided empirical support for the clinically derived conceptual framework that defines the five domains of cerebellar neuropsychiatry. Sub-analyses of the individual domains supported the overshoot-undershoot dichotomy. Convergence between our
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